Featured Research

from universities, journals, and other organizations

High-dose Ibuprofen May Slow Cystic Fibrosis Lung Disease -- Especially In Children

Date:
October 18, 2007
Source:
John Wiley & Sons, Inc.
Summary:
The most important clinical problem for people with cystic fibrosis is inflammation of their lungs. The inflammation then plays a role in further damaging the tissues. Consequently, people have wondered whether giving non-steroidal anti-inflammatory drugs (NSAIDs) to patients with CF will reduce lung inflammation. Long-term high-dose ibuprofen may slow the rate of decline in lung function in children with cystic fibrosis when treatment is started under the age of 13.

The most important clinical problem for people with cystic fibrosis (CF) is inflammation of their lungs. The inflammation then plays a role in further damaging the tissues. Consequently, people have wondered whether giving non-steroidal anti-inflammatory drugs (NSAIDs) to patients with CF will reduce lung inflammation.

Related Articles


This updated Cochrane Review supports the intriguing suggestion that long-term high-dose ibuprofen slows the rate of decline in lung function in children when treatment is started under the age of 13.

The Review now includes new data from a large Canadian multi-centre study, which doubled the number of participants that the researchers could analyse, and in particular, added a large number of children. "The results now show that high-dose ibuprofen may slow down the rate at which the lung function of a child with CF deteriorates. By slowing the rate of deterioration, high-dose ibuprofen can contribute to longer and healthier lives for children with Cystic Fibrosis," said lead researcher Dr Larry Lands, who works in the Department of Pediatrics at Montreal Children's Hospital.

"High-dose ibuprofen, a relatively inexpensive treatment, requires medical supervision, but is generally well-tolerated. Further work is ongoing in my laboratory on the mechanisms of action of high-dose ibuprofen, so that more targeted and potent therapies can be developed," said Lands.

The long-term effects of prolonged use of high doses of NSAIDs have yet to be determined. This treatment is not currently recommended for routine use and patients receiving the therapy should do so under the supervision of a specialist CF Centre. However, future research could lead to real improvements in patients' lives.


Story Source:

The above story is based on materials provided by John Wiley & Sons, Inc.. Note: Materials may be edited for content and length.


Cite This Page:

John Wiley & Sons, Inc.. "High-dose Ibuprofen May Slow Cystic Fibrosis Lung Disease -- Especially In Children." ScienceDaily. ScienceDaily, 18 October 2007. <www.sciencedaily.com/releases/2007/10/071016195927.htm>.
John Wiley & Sons, Inc.. (2007, October 18). High-dose Ibuprofen May Slow Cystic Fibrosis Lung Disease -- Especially In Children. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2007/10/071016195927.htm
John Wiley & Sons, Inc.. "High-dose Ibuprofen May Slow Cystic Fibrosis Lung Disease -- Especially In Children." ScienceDaily. www.sciencedaily.com/releases/2007/10/071016195927.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Nurse Nina Pham Cured of Ebola

Texas Nurse Nina Pham Cured of Ebola

AFP (Oct. 25, 2014) — An American nurse who contracted Ebola while caring for a Liberian patient in Texas has been declared free of the virus and will leave the hospital. Duration: 01:01 Video provided by AFP
Powered by NewsLook.com
IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) — IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) — A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) — The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins