Featured Research

from universities, journals, and other organizations

Emergence Of Recombinant Forms Of HIV: Dynamics And Scaling

Date:
October 30, 2007
Source:
Public Library of Science
Summary:
The emergence of drug resistant forms of HIV often underlies the failure of current antiretroviral therapies for HIV infection. Specific mutations in the HIV genome confer resistance to individual drugs. A new model provides a framework for predicting the development of multi-drug resistance in HIV patients.

The emergence of drug resistant forms of HIV often underlies the failure of current antiretroviral therapies for HIV infection. Specific mutations in the HIV genome confer resistance to individual drugs.

Related Articles


Recombination, a process similar to sexual reproduction in higher organisms, can accelerate the accumulation of resistance mutations by mixing the contents of distinct viral genomes and expedite the failure of therapy.

The dynamics of the emergence of recombinant forms of HIV in infected individuals remains poorly understood.

In a new study* researchers Suryavanshi and Dixit from the Indian Institute of Science, Bangalore, India present a new model of HIV dynamics that provides a detailed account of the emergence and growth of recombinant forms of HIV following infection with diverse viral genomes.

Analysis of experimental data using the model establishes the high rate of HIV recombination and elucidates the origins of scaling relationships that link the relative prevalence of recombinant forms of HIV to the overall extent of infection.

The model provides a framework for predicting the development of multi-drug resistance in HIV patients.

*Citation: Suryavanshi GW, Dixit NM (2007) Emergence of recombinant forms of HIV: Dynamics and scaling. PLoS Comput Biol 3(10): e205. doi:10.1371/journal.pcbi.0030205 (October 26, 2007)


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Cite This Page:

Public Library of Science. "Emergence Of Recombinant Forms Of HIV: Dynamics And Scaling." ScienceDaily. ScienceDaily, 30 October 2007. <www.sciencedaily.com/releases/2007/10/071026095123.htm>.
Public Library of Science. (2007, October 30). Emergence Of Recombinant Forms Of HIV: Dynamics And Scaling. ScienceDaily. Retrieved November 24, 2014 from www.sciencedaily.com/releases/2007/10/071026095123.htm
Public Library of Science. "Emergence Of Recombinant Forms Of HIV: Dynamics And Scaling." ScienceDaily. www.sciencedaily.com/releases/2007/10/071026095123.htm (accessed November 24, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, November 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Winter Can Cause Depression — Here's How To Combat It

Winter Can Cause Depression — Here's How To Combat It

Newsy (Nov. 23, 2014) Millions of American suffer from seasonal depression every year. It can lead to adverse health effects, but there are ways to ease symptoms. Video provided by Newsy
Powered by NewsLook.com
Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com
WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins