Featured Research

from universities, journals, and other organizations

Environmental Toxins May Limit Fertility In Offspring

Date:
November 22, 2007
Source:
University of Toronto
Summary:
Mothers who are exposed to certain toxic environmental compounds prior to pregnancy could limit their offspring's fertility. PAHs -- a widespread pollutant -- accumulate in the body's breast and fatty tissues before pregnancy and are later released into the blood during pregnancy, affecting the fetus.

Mothers who are exposed to certain toxic environmental compounds prior to pregnancy could limit their offspring’s fertility, says a new study by researchers at U of T and Mount Sinai Hospital’s Samuel Lunenfeld Research Institute.

The study provides evidence derived from a mouse model that exposure to the compounds called polycyclic aromatic hydrocarbons (PAHs) prior to conceiving and when lactating reduces the number of eggs in the ovaries of female offspring by two-thirds. PAHs are known carcinogens and one of the most widespread organic pollutants. The compounds are found in cigarette smoke, car exhaust, fumes from wood stoves and in charred and smoked foods.

“The impact of this research is significant,” said Professor Jim Woodgett of medical biophysics and Lunenfeld’s director of research. “While the anti-smoking message is clear, these findings serve as a preventative measure for all Canadians and should raise awareness of common environmental toxins.”

PAHs accumulate in the body’s breast and fatty tissues before pregnancy and are later released into the blood during pregnancy, affecting the fetus.

“While young girls and women may not have thought about their reproductive future, exposure to these toxins now may reduce the fertility of their children,” said Professor Andrea Jurisicova of obstetrics and gynecology, lead author of the study and Canada Research Chair in Molecular and Reproductive Medicine at the Lunenfeld.

The reduction of eggs in a woman’s ovaries can lead to premature menopause which not only limits reproduction but is also associated with osteoporosis, heart disease, stroke and depression.

“This kind of research has important potential implications for future generations. The findings underline the importance of funding and designing cohort and other epidemiologic studies to assess the reproductive and child health effects of exposure to PAHs and other environmental toxins in human populations,” said Dr. Michael Kramer, scientific director of the Canadian Institutes for Health Research’s Institute of Human Development, Child and Youth.

This research was published in the Dec. 3 issue of The Journal of Clinical Investigation.


Story Source:

The above story is based on materials provided by University of Toronto. Note: Materials may be edited for content and length.


Cite This Page:

University of Toronto. "Environmental Toxins May Limit Fertility In Offspring." ScienceDaily. ScienceDaily, 22 November 2007. <www.sciencedaily.com/releases/2007/11/071121172259.htm>.
University of Toronto. (2007, November 22). Environmental Toxins May Limit Fertility In Offspring. ScienceDaily. Retrieved July 29, 2014 from www.sciencedaily.com/releases/2007/11/071121172259.htm
University of Toronto. "Environmental Toxins May Limit Fertility In Offspring." ScienceDaily. www.sciencedaily.com/releases/2007/11/071121172259.htm (accessed July 29, 2014).

Share This




More Health & Medicine News

Tuesday, July 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Ebola Virus Threatens West Africa

Deadly Ebola Virus Threatens West Africa

AP (July 28, 2014) West African nations and international health organizations are working to contain the largest Ebola outbreak in history. It's one of the deadliest diseases known to man, but the CDC says it's unlikely to spread in the U.S. (July 28) Video provided by AP
Powered by NewsLook.com
$15B Deal on Vets' Health Care Reached

$15B Deal on Vets' Health Care Reached

AP (July 28, 2014) A bipartisan deal to improve veterans health care would authorize at least $15 billion in emergency spending to fix a veterans program scandalized by long patient wait times and falsified records. (July 28) Video provided by AP
Powered by NewsLook.com
Two Americans Contract Ebola in Liberia

Two Americans Contract Ebola in Liberia

Reuters - US Online Video (July 28, 2014) Two American aid workers in Liberia test positive for Ebola while working to combat the deadliest outbreak of the virus ever. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins