Featured Research

from universities, journals, and other organizations

Toward A Rosetta Stone For Microbes' Secret Language

Date:
December 31, 2007
Source:
American Chemical Society
Summary:
Scientists are on the verge of decoding the special chemical language that bacteria use to "talk" to each other, British researchers report. That achievement could lead to new treatments for antibiotic-resistant bacteria, including so-called superbugs that infect more than 90,000 people in the United States each year, they note.

Decoding the chemical language of bacteria will help researchers fight antibiotic-resistant infections and dangerous biofilms (shown) that foul medical implants.
Credit: USDA

Scientists are on the verge of decoding the special chemical language that bacteria use to "talk" to each other, British researchers report. That achievement could lead to new treatments for antibiotic-resistant bacteria, including so-called superbugs that infect more than 90,000 people in the United States each year, they note.

Related Articles


David Spring, Martin Welch, and James T. Hodgkinson explain that researchers long have known that bacteria communicate with each other. Microbes release small molecules that enable millions of individuals in a population to coordinate their behavior.

Disease-causing bacteria use this language to decide when to infect a person or other host. Decoding the structure and function of compounds involved in this elaborate signaling process, known as "quorum sensing," could lead to new medicines to block the signals and prevent infections.

The report describes development of a group of powerful compounds, called N-acylated homoserine lactone (AHL) analogues that are effective against a broad-range of bacterial types, including those that cause diseases in humans.

These compounds are "some of the most potent synthetic modulators of quorum sensing" identified to date, they say. In addition to showing promise for fighting antibiotic-resistant infections, the compounds may help prevent the growth of biofilms that foul medical implants and cause tooth decay and gum disease, the scientists note.

The commentary article, "Learning the Language of Bacteria," is published in the November issue of ACS Chemical Biology.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Cite This Page:

American Chemical Society. "Toward A Rosetta Stone For Microbes' Secret Language." ScienceDaily. ScienceDaily, 31 December 2007. <www.sciencedaily.com/releases/2007/12/071210094701.htm>.
American Chemical Society. (2007, December 31). Toward A Rosetta Stone For Microbes' Secret Language. ScienceDaily. Retrieved February 1, 2015 from www.sciencedaily.com/releases/2007/12/071210094701.htm
American Chemical Society. "Toward A Rosetta Stone For Microbes' Secret Language." ScienceDaily. www.sciencedaily.com/releases/2007/12/071210094701.htm (accessed February 1, 2015).

Share This


More From ScienceDaily



More Plants & Animals News

Sunday, February 1, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Nanoscale Sensor Could Help Wine Producers and Clinical Scientists

Nanoscale Sensor Could Help Wine Producers and Clinical Scientists

Reuters - Innovations Video Online (Jan. 30, 2015) A nanosensor that mimics the oral effects and sensations of drinking wine has been developed by Danish and Portuguese researchers. Jim Drury saw it in operation. Video provided by Reuters
Powered by NewsLook.com
Dog-Loving Astronaut Wins Best Photo of 2015

Dog-Loving Astronaut Wins Best Photo of 2015

Buzz60 (Jan. 30, 2015) Retired astronaut and television host, Leland Melvin, snuck his dogs into the NASA studio so they could be in his official photo. As Mara Montalbano (@maramontalbano) shows us, the secret is out. Video provided by Buzz60
Powered by NewsLook.com
U.S. Wants to Analyze DNA from 1 Million People

U.S. Wants to Analyze DNA from 1 Million People

Reuters - US Online Video (Jan. 30, 2015) The U.S. has proposed analyzing genetic information from more than 1 million American volunteers to learn how genetic variants affect health and disease. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Rarest Cat on Planet Caught Attacking Monkeys on Camera

Rarest Cat on Planet Caught Attacking Monkeys on Camera

Buzz60 (Jan. 30, 2015) An African Golden Cat, the rarest large cat on the planet was recently caught on camera by scientists trying to study monkeys. The cat comes out of nowhere to attack those monkeys. Patrick Jones (@Patrick_E_Jones) has the rest. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins