Featured Research

from universities, journals, and other organizations

Cracking The Code Of Bird Flu Time Bomb

Date:
February 4, 2008
Source:
Griffith University
Summary:
Researchers have developed a technique to 'crack-the-code' of the deadly H5N1 avian influenza virus. It will enable influenza virus specialists and drug researchers to interrogate one of the virus' key surface proteins without risk of infection.

Researchers at Griffith University Institute for Glycomics, Queensland led by Professor Mark von Itzstein have developed a technique to 'crack-the-code' of the deadly H5N1 avian influenza virus.
Credit: Image courtesy of Griffith University

Researchers at Griffith University Institute for Glycomics, Queensland led by Professor Mark von Itzstein have developed a technique to 'crack-the-code' of the deadly H5N1 avian influenza virus.

It will enable influenza virus specialists and drug researchers to interrogate one of the virus’ key surface proteins without risk of infection.

This approach will enable the rapid identification of avian and other influenza viruses that have attained the capacity to recognize human receptors and therefore acquired the potential for easy human-to-human transmission.

The Griffith team collaborated with an international project partner team at the Hong Kong University-Institut Pasteur led by Professor Malik Peiris who developed a method to insert the deadly bird flu’s H5 protein in a harmless vehicle called a 'virus-like particle'.

"To better interrogate a virus protein, researchers need to be able to observe and monitor the way it functions when associated with a virus particle," Professor von Itzstein said.

"It's similar to the way it would be difficult to work out how a gun functions by only studying a bullet."

The use of these virus-like particles as a vehicle for the virus protein enables researchers to work without the need for high-containment laboratory procedures mandatory for handling live virus.

Journal reference: Avian Influenza H5-Containing Virus-Like Particles (VLPs): Host-Cell Receptor Specificity by STD NMR Spectroscopy(p NA). Thomas Haselhorst, Jean-Michel Garcia, Tasneem Islam, Jimmy C. C. Lai, Faith J. Rose, John M. Nicholls, J. S. Malik Peiris, Mark von Itzstein. Angewandte Chemie International Edition. Published Online: Jan 29 2008. DOI: 10.1002/anie.200704872


Story Source:

The above story is based on materials provided by Griffith University. Note: Materials may be edited for content and length.


Cite This Page:

Griffith University. "Cracking The Code Of Bird Flu Time Bomb." ScienceDaily. ScienceDaily, 4 February 2008. <www.sciencedaily.com/releases/2008/02/080202211638.htm>.
Griffith University. (2008, February 4). Cracking The Code Of Bird Flu Time Bomb. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/2008/02/080202211638.htm
Griffith University. "Cracking The Code Of Bird Flu Time Bomb." ScienceDaily. www.sciencedaily.com/releases/2008/02/080202211638.htm (accessed April 19, 2014).

Share This



More Health & Medicine News

Saturday, April 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com
Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins