Featured Research

from universities, journals, and other organizations

Ingredient In Yellow Curry Can Reduce Heart Enlargement And May Prevent Heart Failure

Date:
February 22, 2008
Source:
University Health Network
Summary:
Eating curcumin, a natural ingredient in the spice turmeric, may dramatically reduce the chance of developing heart failure, researchers have discovered. Researchers found when the herb is given orally to a variety of mouse models with enlarged hearts (hypertrophy), it can prevent and reverse hypertrophy, restore heart function and reduce scar formation. The healing properties of turmeric have been well known in eastern cultures for some time. The herb has been used in traditional Indian and Chinese medicine to reduce scar formation. For example, when there is a cut or a bruise, the home remedy is to reach for turmeric powder because it can help to heal without leaving a bad scar.

Turmeric. Eating curcumin, a natural ingredient in the spice turmeric, may dramatically reduce the chance of developing heart failure.
Credit: iStockphoto/Nilesh Bhange

Eating curcumin, a natural ingredient in the spice turmeric, may dramatically reduce the chance of developing heart failure, researchers at the Peter Munk Cardiac Centre of the Toronto General Hospital have discovered.

In a study entitled, “Curcumin prevents and reverses murine cardiac hypertrophy,” published in the February edition of the Journal of Clinical Investigation, researchers found when the herb is given orally to a variety of mouse models with enlarged hearts (hypertrophy), it can prevent and reverse hypertrophy, restore heart function and reduce scar formation.

The healing properties of turmeric have been well known in eastern cultures for some time. The herb has been used in traditional Indian and Chinese medicine to reduce scar formation. For example, when there is a cut or a bruise, the home remedy is to reach for turmeric powder because it can help to heal without leaving a bad scar.

Unlike most natural compounds whose effects are minimal, curcumin works directly in the cell nucleus by preventing abnormal unraveling of the chromosome under stress, and preventing excessive abnormal protein production.

“Curcumin’s ability to shut off one of the major switches right at the chromosome source where the enlargement and scarring genes are being turned on is impressive,” says Dr. Peter Liu, cardiologist in the Peter Munk Cardiac Centre and Scientific Director at the Canadian Institutes of Health Research – Institute of Circulatory and Respiratory Health. However Dr. Liu cautions that moderation is important, “the beneficial effects of curcumin are not strengthened by eating more of it.”

Dr. Liu, who holds the Heart and Stroke Foundation’s Polo Chair Professor in Medicine and Physiology at the University of Toronto, says that since curcumin is a naturally occurring compound that is readily available at a low cost, it might be a safe and effective means of preventing heart failure in the future.

“Whether you are young or old; male or female; the larger your heart is, the higher your risk is for developing heart attacks or heart failure in the future. However, until clinical trials are done, we don’t recommend patients to take curcumin routinely. You are better off to take action today by lowering blood pressure, reducing cholesterol, exercising and healthy eating,” says Dr. Liu.

If clinical trials of curcumin support initial findings of heart enlargement prevention, it may offer hope for millions of patients with heart enlargement in a relatively safe and inexpensive manner. Curcumin-based treatments are currently in clinical trials for pancreatic and colorectal cancer patients with promising results.

This study was funded by the Heart and Stroke Foundation and the Canadian Institutes of Health Research.


Story Source:

The above story is based on materials provided by University Health Network. Note: Materials may be edited for content and length.


Cite This Page:

University Health Network. "Ingredient In Yellow Curry Can Reduce Heart Enlargement And May Prevent Heart Failure." ScienceDaily. ScienceDaily, 22 February 2008. <www.sciencedaily.com/releases/2008/02/080221173235.htm>.
University Health Network. (2008, February 22). Ingredient In Yellow Curry Can Reduce Heart Enlargement And May Prevent Heart Failure. ScienceDaily. Retrieved September 18, 2014 from www.sciencedaily.com/releases/2008/02/080221173235.htm
University Health Network. "Ingredient In Yellow Curry Can Reduce Heart Enlargement And May Prevent Heart Failure." ScienceDaily. www.sciencedaily.com/releases/2008/02/080221173235.htm (accessed September 18, 2014).

Share This



More Health & Medicine News

Thursday, September 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Cost of Ebola

The Cost of Ebola

Reuters - Business Video Online (Sep. 18, 2014) As Sierra Leone prepares for a three-day "lockdown" in its latest bid to stem the spread of Ebola, Ciara Lee looks at the financial implications of fighting the largest ever outbreak of the disease. Video provided by Reuters
Powered by NewsLook.com
What HealthKit Bug Means For Your iOS Fitness Apps

What HealthKit Bug Means For Your iOS Fitness Apps

Newsy (Sep. 18, 2014) Apple has delayed the launch of the HealthKit app platform, citing a bug. Video provided by Newsy
Powered by NewsLook.com
Residents Vaccinated as Haiti Fights Cholera Epidemic

Residents Vaccinated as Haiti Fights Cholera Epidemic

AFP (Sep. 18, 2014) Haitians receive the second dose of the vaccine against cholera as part of the UN's vaccination campaign. Duration: 00:34 Video provided by AFP
Powered by NewsLook.com
Raw: Elephant Undergoes Surgery in Tbilisi Zoo

Raw: Elephant Undergoes Surgery in Tbilisi Zoo

AP (Sep. 18, 2014) Grand the elephant has successfully undergone surgery to remove a portion of infected tusk at Tbilisi Zoo in Georgia. British veterinary surgeons used an electric drill to extract the infected piece. (Sept. 18) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins