Featured Research

from universities, journals, and other organizations

New Industrial-scale Process For Making Big Molecules With A Big Future

Date:
March 20, 2008
Source:
American Chemical Society
Summary:
Scientists are reporting discovery of a new method that will enable manufacturers to produce industrial-size batches of dendrimers for the first time. Dendrimers are giant molecules with tree-like branches with a range of potentially valuable commercial and industrial applications. Dendrimers can be produced in custom-designed shapes, sizes, structures and weights suitable for specific uses.

Enormous molecules called dendrimers could serve a variety of functions, including improving drug delivery to materials. Scientists report a method to manufacture them on an industrial scale for the first time.
Credit: Courtesy of the American Chemical Society

Scientists are reporting discovery of a new method that will enable manufacturers to produce industrial-size batches of dendrimers for the first time. Dendrimers are giant molecules with tree-like branches with a range of potentially valuable commercial and industrial applications.

Dendrimers can be produced in custom-designed shapes, sizes, structures and weights suitable for specific uses. Those potential applications range from drug delivery and gene transfer to new materials, coatings, sensors, and herbicides. But because they require multiple steps to make, dendrimers are difficult to produce on an industrial scale.

In their new study, Abdellatif Chouai and Eric E. Simanek describe a practical large-scale synthesis of dendrimers that sidestep this barrier. Their method yields a so-called "uncommitted intermediate," a dendrimer scaffolding that can be built upon in countless ways. This intermediate "can be elaborated into a wealth of diagnostic and therapeutic dendrimers -- some of which are currently being explored in our laboratory," the researchers add.

Journal reference: "Kilogram-Scale Synthesis of a Second-Generation Dendrimer Based on 1,3,5-Triazine Using Green and Industrially Compatible Methods with a Single Chromatographic Step". The Journal of Organic Chemistry. March 21, 2008. (http://dx.doi.org/10.1021/jo702462t)


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Cite This Page:

American Chemical Society. "New Industrial-scale Process For Making Big Molecules With A Big Future." ScienceDaily. ScienceDaily, 20 March 2008. <www.sciencedaily.com/releases/2008/03/080317114243.htm>.
American Chemical Society. (2008, March 20). New Industrial-scale Process For Making Big Molecules With A Big Future. ScienceDaily. Retrieved September 2, 2014 from www.sciencedaily.com/releases/2008/03/080317114243.htm
American Chemical Society. "New Industrial-scale Process For Making Big Molecules With A Big Future." ScienceDaily. www.sciencedaily.com/releases/2008/03/080317114243.htm (accessed September 2, 2014).

Share This




More Matter & Energy News

Tuesday, September 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Australian Airlines Relax Phone Ban Too

Australian Airlines Relax Phone Ban Too

Reuters - Business Video Online (Aug. 26, 2014) Qantas and Virgin say passengers can use their smartphones and tablets throughout flights after a regulator relaxed a ban on electronic devices during take-off and landing. As Hayley Platt reports the move comes as the two domestic rivals are expected to post annual net losses later this week. Video provided by Reuters
Powered by NewsLook.com
Hurricane Marie Brings Big Waves to California Coast

Hurricane Marie Brings Big Waves to California Coast

Reuters - US Online Video (Aug. 26, 2014) Huge waves generated by Hurricane Marie hit the Southern California coast. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Chinese Researchers Might Be Creating Supersonic Submarine

Chinese Researchers Might Be Creating Supersonic Submarine

Newsy (Aug. 26, 2014) Chinese researchers have expanded on Cold War-era tech and are closer to building a submarine that could reach the speed of sound. Video provided by Newsy
Powered by NewsLook.com
Breakingviews: India Coal Strained by Supreme Court Ruling

Breakingviews: India Coal Strained by Supreme Court Ruling

Reuters - Business Video Online (Aug. 26, 2014) An acute coal shortage is likely to be aggravated as India's supreme court declared government coal allocations illegal, says Breakingviews' Peter Thal Larsen. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins