Featured Research

from universities, journals, and other organizations

Taking Action Against PVL-producing Strains Of Staphylococcus Aureus

Date:
April 3, 2008
Source:
Society for General Microbiology
Summary:
Lots of work is being done to recognize and control infections such as community acquired MRSA and the UK is learning from situations in community and health care settings both here and abroad to stay ahead of the game, according to UK scientists.

Lots of work is being done to recognise and control infections such as community acquired MRSA and the UK is learning from situations in community and healthcare settings both here and abroad to stay ahead of the game, according to scientists presenting at the Society for General Microbiology's 162nd meeting.

Related Articles


Some strains of Staphylococcus aureus produce a potent toxin called Panton-Valentine leukocidin (PVL). PVL-Staphylococcus aureus (PVL-SA) usually causes skin and soft tissue infections, including boils and abcesses. More rarely it can cause serious diseases such as necrotising haemorrhagic pneumonia, which has been associated with a high mortality rate.

"Although several other countries have encountered widespread problems with PVL-related disease, infections caused by PVL S. aureus (including PVL MRSA) remain uncommon in the UK. Nonetheless we need to keep the situation under constant review," says Dr Angela Kearns from the Health Protection Agency. Tests carried out at the Health Protection Agency's Staphylococcus Reference Laboratory show that around 2% of all Staphylococcus aureus strains produce the PVL toxin.

"The HPA, working with other healthcare professionals, is in the process of updating guidance on PVL Staphylococcus aureus infection in the UK," says Dr Kearns. "This will provide healthcare professionals with advice to assist the recognition, investigation and management of PVL-SA cases."

To date, most strains of S. aureus that produce the PVL toxin in the UK have been sensitive to a range of antibiotics, including methicillin. These strains are called methicillin sensitive S. aureus (MSSA). In North America, strains of PVL Staphylococcus aureus, most notably the USA300 clone, have been spreading in the community and are resistant to methicillin. USA300 has become endemic in some US hospitals. In contrast, this strain has rarely been seen in England and Wales: 40 cases were identified during a two year study carried out in 2004/5 and most occurred in the community.

Since 2003, the HPA has actively been encouraging the referral of samples from cases of suspected PVL-related disease. Following these initiatives, 224 PVL-SA infections were identified in England and Wales in 2005; 117 (52%) of these were PVL-MRSA (so-called community-associated MRSA). In 2006, 496 PVL-SA were identified, 159 (32%) of which were PVL-MRSA. These figures show a small (0.4-fold) increase in the number of PVL-MRSA occurring nationally between 2005 and 2006.

"The risk to the UK general public of becoming infected with PVL-S. aureus is small but we must not be complacent," says Dr Kearns. "The Agency is actively working alongside healthcare colleagues to raise awareness of PVL S. aureus, as well as ensuring appropriate research continues to monitor trends in infection."

"These PVL strains shouldn't be confused with the hospital strains of MRSA that do not produce the PVL toxin and are more commonly associated with causing wound infections and blood-poisoning in elderly hospitalised patients," says Dr Kearns.

"Some of these infections are unavoidable, but we can help to minimise their impact by building on the wealth of knowledge we have from dealing with the hospital adapted strains of MRSA such as employing good hygiene measures which include proper cleansing and disinfection of cuts and minor wounds."


Story Source:

The above story is based on materials provided by Society for General Microbiology. Note: Materials may be edited for content and length.


Cite This Page:

Society for General Microbiology. "Taking Action Against PVL-producing Strains Of Staphylococcus Aureus." ScienceDaily. ScienceDaily, 3 April 2008. <www.sciencedaily.com/releases/2008/03/080331223758.htm>.
Society for General Microbiology. (2008, April 3). Taking Action Against PVL-producing Strains Of Staphylococcus Aureus. ScienceDaily. Retrieved December 18, 2014 from www.sciencedaily.com/releases/2008/03/080331223758.htm
Society for General Microbiology. "Taking Action Against PVL-producing Strains Of Staphylococcus Aureus." ScienceDaily. www.sciencedaily.com/releases/2008/03/080331223758.htm (accessed December 18, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, December 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
Why Your Boss Should Let You Sleep In

Why Your Boss Should Let You Sleep In

Newsy (Dec. 17, 2014) According to research out of the University of Pennsylvania, waking up for work is the biggest factor that causes Americans to lose sleep. Video provided by Newsy
Powered by NewsLook.com
Flu Outbreak Closing Schools in Ohio

Flu Outbreak Closing Schools in Ohio

AP (Dec. 17, 2014) A wave of flu illnesses has forced some Ohio schools to shut down over the past week. State officials confirmed one pediatric flu-related death, a 15-year-old girl in southern Ohio. (Dec. 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins