Featured Research

from universities, journals, and other organizations

What Are The Concerns For People With Epilepsy As They Age?

Date:
April 16, 2008
Source:
Wiley-Blackwell
Summary:
For people with chronic epilepsy, little is known about the impact of aging on the course of cognitive and brain health, the prevalence of clinical disorders of aging (mild cognitive impairment, dementia), or the disease burdens and risk factors associated with abnormal cognitive and brain aging. A new article presents data that suggest several reasons for concern.

For people with chronic epilepsy, little is known about the impact of aging on the course of cognitive and brain health, the prevalence of clinical disorders of aging (mild cognitive impairment, dementia), or the disease burdens and risk factors associated with abnormal cognitive and brain aging. A new article presents data that suggest several reasons for concern.

Numerous cognitive deficits, neuroimaging abnormalities and psychiatric comorbidities have been well characterized in younger persons with chronic epilepsy, with evidence of progression of these problems in some patients by middle age. People with chronic epilepsy have been exposed to several influences that may place them at increased risk for accelerated cognitive and brain aging, including: treatment with medications now known to adversely affect cholesterol, folate and glucose metabolism; increased rates of vascular disease risk factors; altered lifestyles that include decreased social interaction and physical inactivity; and elevated inflammatory markers.

“The cognitive status of persons who have lived with epilepsy for a long time is unclear,” says Bruce P. Hermann, lead author of the study. “Because persons with epilepsy carry other risk factors for abnormal cognitive and brain aging, there should be great concern regarding the lack of knowledge about their cognitive and brain status in older years.”

Previous research has identified numerous risk factors for abnormal cognitive aging and dementia in the general population, including vascular, inflammatory and lifestyle factors. Many of these factors are overrepresented in epilepsy, but not examined in relationship to cognitive and brain aging in epilepsy. This oversight is important given the epidemiological evidence that risk exposure and cognitive abnormalities in midlife represent critical predictors of eventual abnormal cognitive and brain aging.

“If these factors exert comparable effects in people with chronic epilepsy, the management of epilepsy must be expanded to aggressively address critical risk factors in order to protect and promote cognitive and brain health,” says Hermann.

This study is published in Epilepsia.


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Cite This Page:

Wiley-Blackwell. "What Are The Concerns For People With Epilepsy As They Age?." ScienceDaily. ScienceDaily, 16 April 2008. <www.sciencedaily.com/releases/2008/04/080416140934.htm>.
Wiley-Blackwell. (2008, April 16). What Are The Concerns For People With Epilepsy As They Age?. ScienceDaily. Retrieved September 20, 2014 from www.sciencedaily.com/releases/2008/04/080416140934.htm
Wiley-Blackwell. "What Are The Concerns For People With Epilepsy As They Age?." ScienceDaily. www.sciencedaily.com/releases/2008/04/080416140934.htm (accessed September 20, 2014).

Share This



More Mind & Brain News

Saturday, September 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Food Addiction Might Be Caused By PTSD

Food Addiction Might Be Caused By PTSD

Newsy (Sep. 18, 2014) New research shows that women who suffer from PTSD are three times more likely to develop a food addiction. Video provided by Newsy
Powered by NewsLook.com
Corporal Punishment on Decline, Debate Renews

Corporal Punishment on Decline, Debate Renews

AP (Sep. 16, 2014) Corporal punishment in the United States is on the decline, but there is renewed debate over its use after Minnesota Vikings running back Adrian Peterson was charged with child abuse. (Sept. 16) Video provided by AP
Powered by NewsLook.com
FDA Eyes Skin Shocks Used at Mass. School

FDA Eyes Skin Shocks Used at Mass. School

AP (Sep. 15, 2014) The FDA is considering whether to ban devices used by the Judge Rotenberg Educational Center in Canton, Massachusetts, the only place in the country known to use electrical skin shocks as aversive conditioning for aggressive patients. (Sept. 15) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins