Featured Research

from universities, journals, and other organizations

Clinical Trial Of Nonsurgical Intervention For Patients With Atrial Fibrillation

Date:
June 19, 2008
Source:
Cedars-Sinai Medical Center
Summary:
Doctors are offering an experimental therapy for atrial fibrillation using the WATCHMAN Left Atrial Appendage System. This is a multicenter Phase II clinical trial with about 60 centers in the U.S. participating in the study.

Doctors at the Cedars-Sinai Heart Institute were among the first in California to offer an experimental therapy for atrial fibrillation using the WATCHMAN® Left Atrial Appendage System. This is a multicenter Phase II clinical trial, and Cedars-Sinai is one of about 60 centers nationwide participating in the study.

the study.

Compared to people with normal heart rhythm, patients who have atrial fibrillation -- the upper chambers of the heart quiver instead of pumping effectively -- have a five-fold increased risk of suffering a clot-related stroke. Blood clots commonly form in the left atrial appendage, a pouch attached to the left atrium, and travel to the brain, blocking the flow of oxygenated blood.

Use of the blood thinner Coumadin (warfarin) has been considered standard medical treatment to reduce the risk of stroke in atrial fibrillation patients, but it is associated with increased risk of bleeding problems. The left atrial appendage can be removed surgically -- it serves little if any useful purpose -- but surgery is not always an option.

Aging, high blood pressure, diabetes and other conditions increase stroke risk in atrial fibrillation patients. Many of these same conditions cause patients to be poor candidates for surgery and long-term blood thinner therapy.

The WATCHMAN® Left Atrial Appendage System, developed by Atritech, Inc., is designed to form a mechanical barrier that seals off the entrance to the appendage and prevents clots from forming. It is threaded to the heart through blood vessels, starting at the groin. Once in place, the umbrella-like device is deployed, plugging the entrance to the appendage, and the catheter is withdrawn.

Atrial fibrillation occurs when faulty nerve impulses cause the atria to beat erratically. Using traditional or minimally invasive operating techniques, surgeons may apply heat or freezing temperatures to interrupt these nerve messages and restore normal rhythm. They also may remove the left atrial appendage as part of the procedure to prevent the possibility of future clot formation.

 

Story Source:

The above story is based on materials provided by Cedars-Sinai Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

Cedars-Sinai Medical Center. "Clinical Trial Of Nonsurgical Intervention For Patients With Atrial Fibrillation." ScienceDaily. ScienceDaily, 19 June 2008. <www.sciencedaily.com/releases/2008/06/080619100418.htm>.
Cedars-Sinai Medical Center. (2008, June 19). Clinical Trial Of Nonsurgical Intervention For Patients With Atrial Fibrillation. ScienceDaily. Retrieved September 30, 2014 from www.sciencedaily.com/releases/2008/06/080619100418.htm
Cedars-Sinai Medical Center. "Clinical Trial Of Nonsurgical Intervention For Patients With Atrial Fibrillation." ScienceDaily. www.sciencedaily.com/releases/2008/06/080619100418.htm (accessed September 30, 2014).

Share This



More Health & Medicine News

Tuesday, September 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How 'Yes Means Yes' Defines Sexual Assault

How 'Yes Means Yes' Defines Sexual Assault

Newsy (Sep. 29, 2014) — Aimed at reducing sexual assaults on college campuses, California has adopted a new law changing the standard of consent for sexual activity. Video provided by Newsy
Powered by NewsLook.com
Scientists May Have Found An Early Sign Of Pancreatic Cancer

Scientists May Have Found An Early Sign Of Pancreatic Cancer

Newsy (Sep. 29, 2014) — Researchers looked at 1,500 blood samples and determined people who developed pancreatic cancer had more branched chain amino acids. Video provided by Newsy
Powered by NewsLook.com
Colo. Doctors See Cluster of Enterovirus Cases

Colo. Doctors See Cluster of Enterovirus Cases

AP (Sep. 29, 2014) — Doctors at the Children's Hospital of Colorado say they have treated over 4,000 children with serious respiratory illnesses since August. Nine of the patients have shown distinct neurological symptoms, including limb weakness. (Sept. 29) Video provided by AP
Powered by NewsLook.com
Dr.'s Unsure of Cause of Fast-Spreading Virus

Dr.'s Unsure of Cause of Fast-Spreading Virus

AP (Sep. 29, 2014) — Doctors at the Children's Hospital of Colorado say they have treated over 4,000 children with serious respiratory illnesses since August. Nine of the patients have shown distinct neurological symptoms, including limb weakness. (Sept. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins