Featured Research

from universities, journals, and other organizations

WHO Panel Recommends Single, Simple Test For New TB Vaccine Trials

Date:
June 30, 2008
Source:
Public Library of Science
Summary:
The World Health Organization Initiative for Vaccine Research recently convened a panel of TB vaccine trial experts to examine the best way of testing immunity in blood taken from people vaccinated with a new TB vaccine. Phase three trials focus on testing whether the vaccines will work to protect people against TB.

The World Health Organization Initiative for Vaccine Research recently convened a panel of TB vaccine trial experts to examine the best way of testing immunity in blood taken from people vaccinated with a new TB vaccine.

"The panel recognised that many new and diverse tuberculosis vaccines are currently under development," says the lead author Professor Hanekom, of the South African TB Vaccine Initiative. "The ability to compare results of how the immune systems of people who received these vaccines have responded would be an important asset for TB vaccine research globally." Previously, it has been difficult to compare results because of differences in laboratory approaches, logistics and diverse populations being tested.

The panel evaluated advantages and disadvantages of many types of immune tests, and made specific recommendations for human trials of new vaccines, which included introducing a single and simple test that is used in all vaccine trials.

"The panel recommended the use of a test that had performed excellently, that could yield informative results, and that could be implemented in even the most remote of field sites," says Professor Hanekom. "It is anticipated that this single and simple test will speed up decision-making on which of the new TB vaccines currently being tested globally will proceed to phase three trials."

Phase three trials focus on testing whether the vaccines will work to protect people against TB. The single and simple test recommended by the panel would allow comparison of results on the human immune response to all new TB vaccines currently being tested by the many research initiatives globally. If implemented, this could shorten the process to find an effective vaccine against TB.


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. Hanekom et al. Immunological Outcomes of New Tuberculosis Vaccine Trials: WHO Panel Recommendations. PLoS Medicine, 2008; 5 (7): e145 DOI: 10.1371/journal.pmed.0050145

Cite This Page:

Public Library of Science. "WHO Panel Recommends Single, Simple Test For New TB Vaccine Trials." ScienceDaily. ScienceDaily, 30 June 2008. <www.sciencedaily.com/releases/2008/06/080630201004.htm>.
Public Library of Science. (2008, June 30). WHO Panel Recommends Single, Simple Test For New TB Vaccine Trials. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/2008/06/080630201004.htm
Public Library of Science. "WHO Panel Recommends Single, Simple Test For New TB Vaccine Trials." ScienceDaily. www.sciencedaily.com/releases/2008/06/080630201004.htm (accessed October 20, 2014).

Share This



More Health & Medicine News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Microneedle Patch Promises Painless Pricks

Microneedle Patch Promises Painless Pricks

Reuters - Innovations Video Online (Oct. 18, 2014) Researchers at The National University of Singapore have invented a new microneedle patch that could offer a faster and less painful delivery of drugs such as insulin and painkillers. Video provided by Reuters
Powered by NewsLook.com
Raw: Nurse Nina Pham Arrives in Maryland

Raw: Nurse Nina Pham Arrives in Maryland

AP (Oct. 17, 2014) The first nurse to be diagnosed with Ebola at a Dallas hospital walked down the stairs of an executive jet into an ambulance at an airport in Frederick, Maryland, on Thursday. Pham will be treated at the National Institutes of Health. (Oct. 16) Video provided by AP
Powered by NewsLook.com
Raw: Cruise Ship Returns to US Over Ebola Fears

Raw: Cruise Ship Returns to US Over Ebola Fears

AP (Oct. 17, 2014) A Caribbean cruise ship carrying a Dallas health care worker who is being monitored for signs of the Ebola virus is heading back to Texas, US, after being refused permission to dock in Cozumel, Mexico. (Oct. 17) Video provided by AP
Powered by NewsLook.com
Spanish Govt: Four Suspected Ebola Cases in Spain Test Negative

Spanish Govt: Four Suspected Ebola Cases in Spain Test Negative

AFP (Oct. 17, 2014) All four suspected Ebola cases admitted to hospitals in Spain on Thursday have tested negative for the deadly virus in a first round of tests, the government said Friday. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins