Featured Research

from universities, journals, and other organizations

Angiotensin Receptor Blockers Are Lower Incidence, Progression Of Alzheimer's Disease

Date:
July 29, 2008
Source:
Boston University
Summary:
Researchers have, for the first time, found that angiotensin receptor blockers -- a particular class of anti-hypertensive medicines -- are associated with a striking decrease in the occurrence and progression of dementia.

Researchers at Boston University School of Medicine (BUSM) have, for the first time, found that angiotensin receptor blockers (ARBs)—a particular class of anti-hypertensive medicines—are associated with a striking decrease in the occurrence and progression of dementia. Data from this study will be presented this weekend (July 27) at the 2008 International Conference on Alzheimer's disease in Chicago.

Related Articles


Using data from the Decision Support System Database of the U.S. Department of Health System Veterans Affairs (with information on more than 5 million people), researchers looked at records from patients using ARBs, and compared them with subjects who had a similar health status, but were taking different medications. They found patients taking ARBs had about a 35-40 percent lower chance of getting Alzheimer's disease or dementia.

The researchers also examined patients who were already suffering from Alzheimer's disease or dementia, and found those subjects had up to a 45 percent lower chance of developing delirium, being admitted to nursing homes or dying. Patients who appeared to benefit particularly well from use of ARBs were those who had experienced strokes before or during the course of their illness.

According to the researchers these results suggest that ARBs might protect against developing Alzheimer's disease and dementia. "For those who already have dementia, use of ARBs might delay deterioration of brain function and help keep patients out of nursing homes," said lead presenter Benjamin Wolozin, MD, PhD, a professor of pharmacology at BUSM. "The study is particularly interesting because we compared the effects of ARBs to other medications used for treating blood pressure or cardiovascular disease. This suggests that ARBs are more effective than other blood pressure and cardiovascular medications for preventing Alzheimer's disease or dementia," he added.

Although the researchers are unsure why ARBs might be so beneficial, they believe one possibility suggested by prior studies on animal models is that ARBs help prevent nerve cell injury from blood vessel damage or help promote nerve cell recovery after blood vessel damage. Damage to blood vessels is thought to reduce brain capacity and promote dementia, so reducing this damage might prevent the occurrence or progression of dementia.

This study was funded by the Retirement Research Foundation and from the Casten Foundation.


Story Source:

The above story is based on materials provided by Boston University. Note: Materials may be edited for content and length.


Cite This Page:

Boston University. "Angiotensin Receptor Blockers Are Lower Incidence, Progression Of Alzheimer's Disease." ScienceDaily. ScienceDaily, 29 July 2008. <www.sciencedaily.com/releases/2008/07/080727224053.htm>.
Boston University. (2008, July 29). Angiotensin Receptor Blockers Are Lower Incidence, Progression Of Alzheimer's Disease. ScienceDaily. Retrieved February 27, 2015 from www.sciencedaily.com/releases/2008/07/080727224053.htm
Boston University. "Angiotensin Receptor Blockers Are Lower Incidence, Progression Of Alzheimer's Disease." ScienceDaily. www.sciencedaily.com/releases/2008/07/080727224053.htm (accessed February 27, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, February 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Cherries, Snap Peas and More Tasty Spring Produce

Cherries, Snap Peas and More Tasty Spring Produce

Buzz60 (Feb. 27, 2015) From sweet cherries to sugar snap peas, spring is the peak season for some of the tastiest and healthiest produce. Krystin Goodwin (@Krystingoodwin) has the best seasonal fruits and veggies to spring in to good health! Video provided by Buzz60
Powered by NewsLook.com
New FDA-Approved Diabetes Medicine Might Save Drugmaker

New FDA-Approved Diabetes Medicine Might Save Drugmaker

Newsy (Feb. 26, 2015) The U.S. Food and Drug Administration approved new diabetes drug Toujeo on Wednesday, a move that might save French drugmaker Sanofi&apos;s profits. Video provided by Newsy
Powered by NewsLook.com
The Best Foods to Battle Stress

The Best Foods to Battle Stress

Buzz60 (Feb. 26, 2015) If you&apos;re dealing with anxiety, there are a few foods that can help. Krystin Goodwin (@krystingoodwin) has the best foods to tame stress. Video provided by Buzz60
Powered by NewsLook.com
The 5 Best Tips to Look Younger Now

The 5 Best Tips to Look Younger Now

Buzz60 (Feb. 26, 2015) Life happens, and we all get older, but forget the pricey anti-aging products and plastic surgery. You can tweak your habits to turn back the hands of time. Krystin Goodwin (@krystingoodwin) has a few simple tips to help you look and feel younger. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins