Featured Research

from universities, journals, and other organizations

Pain Appears Common Among Patients With Parkinson's Disease

Date:
September 11, 2008
Source:
JAMA and Archives Journals
Summary:
Pain appears to be more common in individuals with Parkinson's disease than in those without, suggesting that pain is associated with the condition, according to a new report.

Pain appears to be more common in individuals with Parkinson's disease than in those without, suggesting that pain is associated with the condition, according to a new report.

Related Articles


"Patients with Parkinson's disease often complain of painful sensations that may involve body parts affected and unaffected by dystonia," or involuntary muscle contractions, the authors write as background information in the article. This pain may resemble cramping or arthritis, or have features of pain caused by nerve damage. "The high frequency of these pain disorders in the general population makes it hard to establish whether pain is more frequent among people with Parkinson's disease than among age-matched controls."

Giovanni Defazio, M.D., Ph.D., of the University of Bari, Italy, and colleagues compared 402 patients with Parkinson's disease to 317 healthy individuals who were the same age. Participants provided information about their current age, the age at which they developed Parkinson's disease, scores on disease rating scales and details regarding any pain that was present at the time of the study and lasted for at least three months.

Overall, pain was more common among Parkinson's disease patients than among controls (281 or 69.9 percent vs. 199 or 62.8 percent). This was mainly attributable to dystonic pain, as rates of pain not associated with dystonia were similar among individuals with Parkinson's disease (267 or 66.4 percent) and those without (199 or 62.8 percent).

"Nevertheless, we observed a significant association between Parkinson's disease and non-dystonic pain, beginning after the onset of parkinsonian symptoms," the authors write. "Cramping and central neuropathic [nervous system–related] pain were more frequent among Parkinson's disease patients than controls. About one-quarter of patients who experienced pain reported pain onset before starting antiparkinsonian therapy."

Basal ganglia, structures deep in the brain that control movement and are damaged in patients with Parkinson's disease, also are involved with pain processing, the authors note. This might account for the increase in pain associated with Parkinson's disease.

"These data support the hypothesis that pain begins at clinical onset of Parkinson's disease or thereafter as a non-motor feature of Parkinson's disease," they conclude. "The findings of this study may have implications for designing studies aimed at understanding pain mechanisms in Parkinson's disease and identifying specific treatment strategies."


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Journal Reference:

  1. Defazio et al. Pain as a Nonmotor Symptom of Parkinson Disease: Evidence From a Case-Control Study. Archives of Neurology, 2008; 65 (9): 1191 DOI: 10.1001/archneurol.2008.2

Cite This Page:

JAMA and Archives Journals. "Pain Appears Common Among Patients With Parkinson's Disease." ScienceDaily. ScienceDaily, 11 September 2008. <www.sciencedaily.com/releases/2008/09/080908185222.htm>.
JAMA and Archives Journals. (2008, September 11). Pain Appears Common Among Patients With Parkinson's Disease. ScienceDaily. Retrieved March 5, 2015 from www.sciencedaily.com/releases/2008/09/080908185222.htm
JAMA and Archives Journals. "Pain Appears Common Among Patients With Parkinson's Disease." ScienceDaily. www.sciencedaily.com/releases/2008/09/080908185222.htm (accessed March 5, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, March 5, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Adults Only Get The Flu Twice A Decade, Researchers Say

Adults Only Get The Flu Twice A Decade, Researchers Say

Newsy (Mar. 4, 2015) Researchers found adults only get the flu about once every five years. Scientists analyzed how a person&apos;s immunity builds up over time as well. Video provided by Newsy
Powered by NewsLook.com
New Hormone Could Protect Against Diabetes And Weight Gain

New Hormone Could Protect Against Diabetes And Weight Gain

Newsy (Mar. 4, 2015) A newly discovered hormone mimics the effects of exercise, protecting against diabetes and weight gain. Video provided by Newsy
Powered by NewsLook.com
Mount Everest Has a Poop Problem

Mount Everest Has a Poop Problem

Buzz60 (Mar. 4, 2015) With no bathrooms to use, climbers of Mount Everest have been leaving human waste on the mountain for years, and it&apos;s becoming a health issue. Mike Janela (@mikejanela) has more. Video provided by Buzz60
Powered by NewsLook.com
The Best Tips to 'Skinny' Your Home

The Best Tips to 'Skinny' Your Home

Buzz60 (Mar. 4, 2015) If you&apos;re looking to reach your health goals this season, there are a few simple tips to help you spring clean your space and improve your nutrition. Krystin Goodwin (@krystingoodwin) has the skinny on keeping a healthy home. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins