Featured Research

from universities, journals, and other organizations

How Bed Bugs Outsmart Poisons Designed To Control Them

Date:
January 12, 2009
Source:
University of Massachusetts Amherst
Summary:
Bed bugs, once nearly eradicated in the built environment, have made a big comeback recently, especially in urban centers such as New York City. In the first study to explain the failure to control certain bed bug populations, toxicologists show that some of these nocturnal blood suckers have developed resistance to pyrethroid insecticides, in particular deltamethrin, that attack their nervous systems.

Bed bugs, once nearly eradicated in the built environment, have made a big comeback recently, especially in urban centers such as New York City. In the first study to explain the failure to control certain bed bug populations, toxicologists at the University of Massachusetts Amherst and Korea’s Seoul National University show that some of these nocturnal blood suckers have developed resistance to pyrethroid insecticides, in particular deltamethrin, that attack their nervous systems.

The study by senior researcher John Clark and colleagues in the current issue of the Journal of Medical Entomology reveals that these pests have evolved to outsmart the latest generation of chemicals used to control them since DDT was banned. In providing this first look at a mechanism, the researchers summarize that diagnostic tools to detect the relevant mutation in bed bug populations have been “urgently needed for effective control and resistance management.”

Specifically, Clark and colleagues found that bed bugs in New York City have acquired mutations in their nerve cells, which blunt the neurotoxic effect of the pyrethroid toxins used against them. The mutations affect sodium channels (resembling pores) in the neurons’ outer membrane, where electrical nerve impulses are produced. In the past, these nervous system poisons could effectively paralyze and kill the bugs, but this is no longer always the case.

Resistance means mutations are acquired over time by selection with pyrethroids, so the neuronal pores no longer respond to their toxic effects. Clark and colleagues found that these pores in New York City bed bugs are now as much as 264 times more resistant to deltamethrin. This means that even if treated, New York City bed bugs go on to suck blood from unsuspecting sleepers for many more nights.

The researchers are not sure how widely this resistance has spread, that is, whether the bugs that infest hotels, apartment buildings and homes in places other than New York City have developed the same type of immunity to chemical control. But as Clark states, “This type of pyrethroid resistance is common in many pest insects and the failure of the pyrethroids to control bed bug populations across the United States and elsewhere indicates that resistance is already widespread.”

For this study, the researchers collected hard-to-control bed bugs from New York City, plus easy-to-control bed bugs from an untreated colony in Florida, Clark explains. The New York population was determined to be highly resistant (264 times more resistant) to deltamethrin compared to the Florida population by contact exposure. Further, they found that resistance was not due to the increased breakdown of deltamethrin (enzymatic metabolism) by the resistant bed bugs but appeared to be due to an insensitive nervous system.

Using molecular techniques, they sequenced genes related to the sodium ion channel’s operation in both groups and identified two mutations found only in the resistant population. Similar mutations have been found in other pyrethroid-resistant insects and are likely the cause of the resistance in bed bugs, Clark and colleagues note. This helps to narrow the focus of the next set of experiments designed to reveal more about the acquired resistance.

There are several kinds of bed bugs but the one best adapted to the human environment is known in Latin as Cimex (“a bug”) lectularius (“lying down at home”), which shows how long they’ve been with us. Bed bugs arrived here with the earliest European visitors. These nocturnal pests feed about once every five to 10 days but are not thought to spread disease. They use two tubes, one to inject an anticoagulant and mild anesthetic, the other to suck blood.


Story Source:

The above story is based on materials provided by University of Massachusetts Amherst. Note: Materials may be edited for content and length.


Cite This Page:

University of Massachusetts Amherst. "How Bed Bugs Outsmart Poisons Designed To Control Them." ScienceDaily. ScienceDaily, 12 January 2009. <www.sciencedaily.com/releases/2009/01/090110090254.htm>.
University of Massachusetts Amherst. (2009, January 12). How Bed Bugs Outsmart Poisons Designed To Control Them. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/2009/01/090110090254.htm
University of Massachusetts Amherst. "How Bed Bugs Outsmart Poisons Designed To Control Them." ScienceDaily. www.sciencedaily.com/releases/2009/01/090110090254.htm (accessed April 19, 2014).

Share This



More Health & Medicine News

Saturday, April 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Nine-Month-Old Baby Can't Open His Mouth

Nine-Month-Old Baby Can't Open His Mouth

Newsy (Apr. 19, 2014) Nine-month-old Wyatt Scott was born with a rare disorder called congenital trismus, which prevents him from opening his mouth. Video provided by Newsy
Powered by NewsLook.com
'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins