Featured Research

from universities, journals, and other organizations

New Evidence That Humans Make Aspirin's Active Principle -- Salicylic Acid

Date:
January 15, 2009
Source:
American Chemical Society
Summary:
Scientists in the United Kingdom are reporting new evidence that humans can make their own salicylic acid (SA) -- the material formed when aspirin breaks down in the body. SA, which is responsible for aspirin's renowned effects in relieving pain and inflammation, may be the first in a new class of bioregulators, according to a new study.

Scientists in the United Kingdom are reporting new evidence that humans can make their own salicylic acid (SA) -- the material formed when aspirin breaks down in the body.
Credit: iStockphoto

Scientists in the United Kingdom are reporting new evidence that humans can make their own salicylic acid (SA) — the material formed when aspirin breaks down in the body. SA, which is responsible for aspirin's renowned effects in relieving pain and inflammation, may be the first in a new class of bioregulators, according to a new study.

In the report, Gwendoline Baxter, Ph.D. and colleagues discuss how their past research revealed that SA exists in the blood of people who have not recently taken aspirin. Vegetarians had much higher levels, almost matching those in patients taking low doses of aspirin. Based on those findings, the researchers previously concluded that this endogenous SA came from the diet, since SA is a natural substance found in fruits and vegetables.

Now the group reports on studies of changes in SA levels in volunteers who took benzoic acid, a substance also found naturally in fruits and vegetables that the body could potentially use to make SA. Their goal was to determine whether the SA found in humans (and other animals) results solely from consumption of fruits and vegetables, or whether humans produce their own SA as a natural agent to fight inflammation and disease. The results reported in the study suggest that people do manufacture SA.

"It is, we suspect, increasingly likely that SA is a biopharmaceutical with a central, broadly defensive role in animals as well as plants," they state. "This simple organic chemical is, we propose, likely to become increasingly recognized as an animal bioregulator, perhaps in a class of its own."


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Paterson et al. Salicylic Acid sans Aspirin in Animals and Man: Persistence in Fasting and Biosynthesis from Benzoic Acid. Journal of Agricultural and Food Chemistry, 2008; 56 (24): 11648 DOI: 10.1021/jf800974z

Cite This Page:

American Chemical Society. "New Evidence That Humans Make Aspirin's Active Principle -- Salicylic Acid." ScienceDaily. ScienceDaily, 15 January 2009. <www.sciencedaily.com/releases/2009/01/090112093330.htm>.
American Chemical Society. (2009, January 15). New Evidence That Humans Make Aspirin's Active Principle -- Salicylic Acid. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2009/01/090112093330.htm
American Chemical Society. "New Evidence That Humans Make Aspirin's Active Principle -- Salicylic Acid." ScienceDaily. www.sciencedaily.com/releases/2009/01/090112093330.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins