Featured Research

from universities, journals, and other organizations

New Tuberculosis Blood Test Is Useful Tool, If Used With Care

Date:
February 26, 2009
Source:
Wiley - Blackwell
Summary:
The newly introduced Interferon-Y release assays (IGRA) is a new group of blood tests that offer many operational advantages over the conventional tuberculin skin tests (TST) -- particularly in the diagnosis of latent tuberculosis (TB).

The newly introduced Interferon-Y release assays (IGRA) is a new group of blood tests that offer many operational advantages over the conventional tuberculin skin tests (TST) -- particularly in the diagnosis of latent tuberculosis (TB).

An editorial published in Respirology by Wiley-Blackwell discusses the role of IGRA in the diagnosis of TB and brings attention to the potential caveats in the application of these new tests.

"IGRA offers many advantages over TST, such as completion of tests in one visit, availability of results within 24 hours, absence of inter and intra-divergence, ability to detect potential immonu-depression and the avoidance of the booster phenomenon. However, their current cost and the need for delivery of fresh blood limits the feasibility of large-scale application in most TB-endemic areas," said author Professor Chi Chiu Leung of the Tuberculosis and Chest Service, Department of Health, Hong Kong.

TB is an ancient disease that remains a major killer in many parts of the world. It is estimated that one out of ten infected immuno-competent individuals will develop the clinical disease in his or her lifetime.

The ultimate purpose of screening for TB infection is to prevent the onset of the disease. Unfortunately, none of the existing tests for TB infection can distinguish between latent infection and active disease.

"While it is generally difficult to interpret a positive test in TB-endemic areas, IGRA may still play an important adjunctive role for the diagnosis of active TB in children. The new tools offer significant advantages over TST, especially in setting with widespread BCG vaccinations after infancy or revaccinations." said Professor Leung.

He added, "With the various intrinsic limitations present in IGRA, added care should be exercised in the application and interpretation of the new tools. Further studies are required to provide definitive answers and allow these new tools to be applied more effectively."

This paper is published in the January 2009 issue of Respirology (Vol. 14, Issue 2).


Story Source:

The above story is based on materials provided by Wiley - Blackwell. Note: Materials may be edited for content and length.


Cite This Page:

Wiley - Blackwell. "New Tuberculosis Blood Test Is Useful Tool, If Used With Care." ScienceDaily. ScienceDaily, 26 February 2009. <www.sciencedaily.com/releases/2009/02/090226082354.htm>.
Wiley - Blackwell. (2009, February 26). New Tuberculosis Blood Test Is Useful Tool, If Used With Care. ScienceDaily. Retrieved October 23, 2014 from www.sciencedaily.com/releases/2009/02/090226082354.htm
Wiley - Blackwell. "New Tuberculosis Blood Test Is Useful Tool, If Used With Care." ScienceDaily. www.sciencedaily.com/releases/2009/02/090226082354.htm (accessed October 23, 2014).

Share This



More Health & Medicine News

Thursday, October 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Working Mother (Oct. 22, 2014) Is your child ready? Video provided by Working Mother
Powered by NewsLook.com
U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

Newsy (Oct. 22, 2014) Now that the U.S. is restricting travel from West Africa, some are dropping questions about a travel ban and instead asking about visa bans. Video provided by Newsy
Powered by NewsLook.com
US to Track Everyone Coming from Ebola Nations

US to Track Everyone Coming from Ebola Nations

AP (Oct. 22, 2014) Stepping up their vigilance against Ebola, federal authorities said Wednesday that everyone traveling into the US from Ebola-stricken nations will be monitored for symptoms for 21 days. (Oct. 22) Video provided by AP
Powered by NewsLook.com
Doctors Help Paralysed Man Walk Again, Patient in Disbelief

Doctors Help Paralysed Man Walk Again, Patient in Disbelief

AFP (Oct. 22, 2014) Polish doctors describe how they helped a paralysed man walk again, with the patient in disbelief at the return of sensation to his legs. Duration: 1:04 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins