Featured Research

from universities, journals, and other organizations

High Prevalence Of Infection With Three Recently Discovered Human Polyomaviruses

Date:
April 3, 2009
Source:
Public Library of Science
Summary:
A majority of the human population has been exposed to newly discovered KI (KIV), WU (WUV), and Merkel cell (MCV) human polyomaviruses, according to a new study. The results, based on antibody measurements in serum samples, also suggest that infection with these viruses occurs early in childhood.

A majority of the human population has been exposed to newly discovered KI (KIV), WU (WUV), and Merkel cell (MCV) human polyomaviruses, according to a new study by researchers at the University of Colorado. The results, based on antibody measurements in serum samples, also suggest that infection with these viruses occurs early in childhood.

For over 30 years, scientists have known about two human polyomaviruses, BKV and JCV. Within the past two years, however, three new viruses have been described that belong to this same virus family. KIV and WUV were detected in nasal secretions, and may be respiratory viruses. MCV was discovered in Merkel Cell carcinomas, a rare skin cancer. Further studies are needed to determine what fraction of the human population has been infected with these viruses and when initial exposure occurs.

In this study, Kean and colleagues tested over 2220 anonymous donor blood samples (more than1500 adult and more than 700 pediatric [< 21 years of age]) They measured antibodies that reacted with specific viral proteins. In addition to KIV, WUV, MCV, BKV, and JCV, two monkey polyomaviruses, SV40 and lymphotropic polyomavirus (LPV), were also studied. Antibodies to LPV were detected in a fraction of people (15%), confirming previous studies suggesting that a relative of this virus may infect humans. The majority of antibodies against SV40 proteins may be attributed to the immune response to BKV. The diseases caused by these viruses remain to be fully described.

The samples and results reported are likely representative of infection in the Denver metropolitan area where they were collected. Future studies will be important to help determine differences in the prevalence of these infections in other geographic areas.


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. Kean JM, Rao S, Wang M, Garcea RL. Seroepidemiology of Human Polyomaviruses. PLoS Pathog, e1000363 DOI: 10.1371/journal.ppat.1000363

Cite This Page:

Public Library of Science. "High Prevalence Of Infection With Three Recently Discovered Human Polyomaviruses." ScienceDaily. ScienceDaily, 3 April 2009. <www.sciencedaily.com/releases/2009/03/090326215052.htm>.
Public Library of Science. (2009, April 3). High Prevalence Of Infection With Three Recently Discovered Human Polyomaviruses. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2009/03/090326215052.htm
Public Library of Science. "High Prevalence Of Infection With Three Recently Discovered Human Polyomaviruses." ScienceDaily. www.sciencedaily.com/releases/2009/03/090326215052.htm (accessed July 22, 2014).

Share This




More Plants & Animals News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Michigan Plant's Goal: Flower and Die

Michigan Plant's Goal: Flower and Die

AP (July 22, 2014) An 80-year-old agave plant, which is blooming for the first and only time at a University of Michigan conservatory, will die when it's done (July 22) Video provided by AP
Powered by NewsLook.com
San Diego Zoo Welcomes New, Rare Rhino Calf

San Diego Zoo Welcomes New, Rare Rhino Calf

Reuters - US Online Video (July 21, 2014) An endangered black rhino baby is the newest resident at the San Diego Zoo. Sasha Salama reports. Video provided by Reuters
Powered by NewsLook.com
Shark Sightings a Big Catch for Cape Tourism

Shark Sightings a Big Catch for Cape Tourism

AP (July 21, 2014) A rise in shark sightings along the shores of Chatham, Massachusetts is driving a surge of eager vacationers to the beach town looking to catch a glimpse of a great white. (July 21) Video provided by AP
Powered by NewsLook.com
$23.6 Billion Awarded To Widow In Smoking Lawsuit

$23.6 Billion Awarded To Widow In Smoking Lawsuit

Newsy (July 20, 2014) Cynthia Robinson claims R.J. Reynolds Tobacco Company hid the health and addiction risks of its products, leading to the death of her husband in 1996. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins