Featured Research

from universities, journals, and other organizations

New Trial Casts Doubt On Role Of Zinc Supplements In Diarrhea Treatment

Date:
May 11, 2009
Source:
BMC Medicine
Summary:
Zinc supplementation can be ineffective in the treatment of diarrhea. A randomized controlled trial has shown that supplementation with either zinc or zinc and copper is no more effective than placebo.

Zinc supplementation can be ineffective in the treatment of diarrhea. A randomised controlled trial published in the open access journal BMC Medicine has shown that supplementation with either zinc or zinc and copper is no more effective than placebo.

Archana Patel, from the Lata Medical Research Foundation, India, led a team of researchers who studied the effects of the different supplements on a group of 808 children in Nagpur, also in India. She said, "The expected beneficial effects of zinc supplementation for acute diarrhea were not observed. Therapeutic zinc or zinc and copper supplementation may not have a universal beneficial impact on the duration of acute diarrhea in children".

The authors found that neither duration of diarrhoea, total stool weight, use of oral rehydration salts nor use of intravenous fluids were affected by supplementation. The authors said, "There could be many reasons for the lack of effect observed in our study. Although our study controlled for baseline serum zinc concentrations, these are not always a reliable measure of body zinc status. As such, baseline zinc deficiency in our subjects may have affected our results. Different diarrhea etiologies and the impact of interactions of zinc with multi-vitamins shown in previous studies may also explain the difference between our study and others that have shown a positive effect."

The authors have called for a re-examination of all available trial data, including this one, to dissect out the potential contributors to heterogeneity of results before zinc can be universally recommended for treatment of acute childhood diarrhea.


Story Source:

The above story is based on materials provided by BMC Medicine. Note: Materials may be edited for content and length.


Journal Reference:

  1. Archana Patel, Michael J Dibley, Manju Mamtani, Neetu Badhoniya and Hemant Kulkarni. Zinc and copper supplementation in acute diarrhea in children: a double-blind randomized controlled trial. BMC Medicine, (in press)

Cite This Page:

BMC Medicine. "New Trial Casts Doubt On Role Of Zinc Supplements In Diarrhea Treatment." ScienceDaily. ScienceDaily, 11 May 2009. <www.sciencedaily.com/releases/2009/05/090504201114.htm>.
BMC Medicine. (2009, May 11). New Trial Casts Doubt On Role Of Zinc Supplements In Diarrhea Treatment. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2009/05/090504201114.htm
BMC Medicine. "New Trial Casts Doubt On Role Of Zinc Supplements In Diarrhea Treatment." ScienceDaily. www.sciencedaily.com/releases/2009/05/090504201114.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins