Featured Research

from universities, journals, and other organizations

New Imaging Technique Reveals Structural Changes In Tourette's

Date:
May 16, 2009
Source:
BMC Neuroscience
Summary:
Magnetization transfer imaging has been used to visualize previously unknown alterations in the cerebral architecture of patients with Tourette's syndrome. The researchers also found a correlation between the extent of some of the structural changes and symptom severity.

Magnetization Transfer Imaging, MTI, has been used to visualize previously unknown alterations in the cerebral architecture of patients with Tourette's syndrome. The researchers also found a correlation between the extent of some of the structural changes and symptom severity.

Related Articles


Kirsten Mόller-Vahl, from Hanover Medical School, led a team of researchers who used normal MRI scanning and the new MTI technique to investigate the brains of 19 Tourette's patients and 20 controls. They identified alterations in the frontal lobe of the Tourette's group that they suggest may be responsible for the pathology of the syndrome. Mόller-Vahl said, "Our in vivo findings, using two sensitive and unbiased techniques, support the hypothesis that alterations in frontostriatal circuitries underlie Tourette's pathology".

The MTI technique used by the researchers has never before been applied to the study of Tourette's. It is a refinement of the nuclear magnetic resonance technique and allows for the detection of changes invisible to conventional MRI scanners. Tissue alterations in comparison to controls were detected in brain areas involved in the selection, programming, initiation, and control of movement. The authors conclude, "We suggest that Tourette's is primarily caused by a dysfunction in prefrontal cortex areas rather than the basal ganglia, as has been previously thought".

Tourette's syndrome is estimated to affect between 1-10 children per 1000 and, although the severity of a person's tics tends to decline with age, as many as 1% of the adult population may have some form of tic disorder. Symptoms include various facial, phonic and other motor tics - the well-known propensity for 'un-voluntary' swearing is in fact relatively uncommon, only affecting about 10% of Tourette's patients.


Story Source:

The above story is based on materials provided by BMC Neuroscience. Note: Materials may be edited for content and length.


Journal Reference:

  1. Kirsten R Muller-Vahl, Jorn Kaufmann, Julian Grosskreutz, Reinhard Dengler, Hinderk M Emrich and Thomas Peschel. Prefrontal and anterior cingulate cortex abnormalities in Tourette Syndrome: evidence from voxel-based morphometry and magnetization transfer imaging. BMC Neuroscience, (in press)

Cite This Page:

BMC Neuroscience. "New Imaging Technique Reveals Structural Changes In Tourette's." ScienceDaily. ScienceDaily, 16 May 2009. <www.sciencedaily.com/releases/2009/05/090511210419.htm>.
BMC Neuroscience. (2009, May 16). New Imaging Technique Reveals Structural Changes In Tourette's. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2009/05/090511210419.htm
BMC Neuroscience. "New Imaging Technique Reveals Structural Changes In Tourette's." ScienceDaily. www.sciencedaily.com/releases/2009/05/090511210419.htm (accessed October 31, 2014).

Share This



More Health & Medicine News

Friday, October 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Melafind: Spotting Melanoma Without a Biopsy

Melafind: Spotting Melanoma Without a Biopsy

Ivanhoe (Oct. 31, 2014) — The MelaFind device is a pain-free way to check suspicious moles for melanoma, without the need for a biopsy. Video provided by Ivanhoe
Powered by NewsLook.com
Battling Multiple Myeloma

Battling Multiple Myeloma

Ivanhoe (Oct. 31, 2014) — The answer isn’t always found in new drugs – repurposing an ‘old’ drug that could mean better multiple myeloma treatment, and hope. Video provided by Ivanhoe
Powered by NewsLook.com
Chronic Inflammation and Prostate Cancer

Chronic Inflammation and Prostate Cancer

Ivanhoe (Oct. 31, 2014) — New information that is linking chronic inflammation in the prostate and prostate cancer, which may help doctors and patients prevent cancer in the future. Video provided by Ivanhoe
Powered by NewsLook.com
Sickle Cell: Stopping Kids’ Silent Strokes

Sickle Cell: Stopping Kids’ Silent Strokes

Ivanhoe (Oct. 31, 2014) — Blood transfusions are proving crucial to young sickle cell patients by helping prevent strokes, even when there is no outward sign of brain injury. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins