Featured Research

from universities, journals, and other organizations

New Strategies For Cell Therapy To Regenerate Damaged Heart

Date:
May 21, 2009
Source:
Basque Research
Summary:
In animal models, stem cells derived from bone marrow and adipose tissue enhance heart function after a cardiac attack.

Research undertaken at the Center for Applied Medical Research (CIMA) and the University Hospital of Navarra has shown that, in animal models, stem cells derived from bone marrow and adipose tissue enhance heart function after a cardiac attack.

In concrete, bone marrow cells act on the damaged tissue, while fatty cells have the ability to transform themselves into both blood vessels and cardiac cells. The results obtained with rats are maintained over a long time period, explained biochemist Mr Manuel Mazo, principal researcher.

When a person suffers a heart attack, the artery feeding the heart is obstructed The affected tissue dies and the scar tissue left des not contract. It is a serious problem as cardiac muscle does not regenerate, with grave consequences for the functional capacity of the heart, a situation which can trigger heart failure, explained the scientist.

Mortality for cardiovascular diseases

Myocardial arrest is a pathology which has one of the highest rates worldwide. In fact, the overall number of cardiovascular illnesses represents 50% of deaths in Europe, according to the world Health Organisation.

For a decade now they have been investigating new strategies of genic therapy and cell therapy that enable the repopulation of the scar tissue in the heart in order to regenerate it. In the opinion of Dr. Manuel Mazo, the data obtained at CIMA suggest that this procedure has a highly important potential in its clinical application.

This is why the effects which are being achieved have to be improved in both animal models as well as in other, multicentre clinical trials. In this way, the future of the research is focused on combining cell therapy and bioengineering, in such a way that genetically modified cells surviving from adverse conditions in the heart are available.


Story Source:

The above story is based on materials provided by Basque Research. Note: Materials may be edited for content and length.


Cite This Page:

Basque Research. "New Strategies For Cell Therapy To Regenerate Damaged Heart." ScienceDaily. ScienceDaily, 21 May 2009. <www.sciencedaily.com/releases/2009/05/090520055517.htm>.
Basque Research. (2009, May 21). New Strategies For Cell Therapy To Regenerate Damaged Heart. ScienceDaily. Retrieved August 21, 2014 from www.sciencedaily.com/releases/2009/05/090520055517.htm
Basque Research. "New Strategies For Cell Therapy To Regenerate Damaged Heart." ScienceDaily. www.sciencedaily.com/releases/2009/05/090520055517.htm (accessed August 21, 2014).

Share This




More Health & Medicine News

Thursday, August 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Newsy (Aug. 21, 2014) An experimental drug used to treat Marburg virus in rhesus monkeys could give new insight into a similar treatment for Ebola. Video provided by Newsy
Powered by NewsLook.com
Cadavers, a Teen, and a Medical School Dream

Cadavers, a Teen, and a Medical School Dream

AP (Aug. 21, 2014) Contains graphic content. He's only 17. But Johntrell Bowles has wanted to be a doctor from a young age, despite the odds against him. He was recently the youngest participant in a cadaver program at the Indiana University NW medical school. (Aug. 21) Video provided by AP
Powered by NewsLook.com
American Ebola Patients Released: What Cured Them?

American Ebola Patients Released: What Cured Them?

Newsy (Aug. 21, 2014) It's unclear whether the American Ebola patients' recoveries can be attributed to an experimental drug or early detection and good medical care. Video provided by Newsy
Powered by NewsLook.com
Lost Brain Cells To Blame For Sleep Problems Among Seniors

Lost Brain Cells To Blame For Sleep Problems Among Seniors

Newsy (Aug. 21, 2014) According to a new study, elderly people might have trouble sleeping because of the loss of a certain group of neurons in the brain. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins