Featured Research

from universities, journals, and other organizations

Fly Larvae Shun The Light

Date:
June 29, 2009
Source:
BioMed Central
Summary:
Drosophila larvae avoid light during the foraging stage of their development. New research shows that both 5-HT (serotonergic) and corazonergic neurons have a role in regulating this behavior.

Drosophila larvae avoid light during the foraging stage of their development. New research shows that both 5-HT (serotonergic) and corazonergic neurons have a role in regulating this behavior.

To identify which neurons modulate the larvae's photobehavior, Verσnica G. Rodriguez Moncalvo and Ana Regina Campos from McMaster University, Ontario, Canada analysed Drosophila larvae which had been genetically engineered to achieve suppressed synaptic transmission in candidate neurons. Muted synaptic transmission can be achieved by targeted expression of tetanus toxin light chain (TNT), as when made in neurons TNT suppresses evoked and spontaneous neurotransmitter release.

The authors looked first at larvae in which dopaminergic, serotonergic and corazonergic neurons had been silenced by using the DOPA decarboxylase (Ddc) promoter to drive TNT expression, and subsequently at larvae expressing constructs with more specific promoters, in which different subsets of Ddc neurons were muted. Larvae with and without the function of these neurons were put through their paces in light and dark conditions.

The results show that inactivation of Ddc neurons increases the aversion to light, both during the foraging phase, when larvae are characteristically photophobic, and the later stages of development, when larvae are usually photoneutral. Both 5-HT neurons and corazonergic neurons, but not dopaminergic neurons, contribute to light-controlled larval locomotion, and this is modulated at least partly by 5-HT neurons located in the brain hemispheres. However, this modulation does not appear to occur at the photoreceptor level and may be mediated by 5-HT1ADro receptors. These findings may provide clues to help identify the target neurons of the serotonin signalling, which the authors believe could be critical for light-controlled movement.

"These findings provide new insights into the function of 5-HT neurons in Drosophila larval behavior, as well as into the mechanisms underlying regulation of larval response to light," says Campos.


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Veronica G Rodriguez Moncalvo and Ana REGINA Campos. Role of serotonergic neurons in the Drosophila larval response to light. BMC Neuroscience, (in press) [link]

Cite This Page:

BioMed Central. "Fly Larvae Shun The Light." ScienceDaily. ScienceDaily, 29 June 2009. <www.sciencedaily.com/releases/2009/06/090622192236.htm>.
BioMed Central. (2009, June 29). Fly Larvae Shun The Light. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2009/06/090622192236.htm
BioMed Central. "Fly Larvae Shun The Light." ScienceDaily. www.sciencedaily.com/releases/2009/06/090622192236.htm (accessed July 31, 2014).

Share This




More Plants & Animals News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Visitors Feel Part of the Pack at Wolf Preserve

Visitors Feel Part of the Pack at Wolf Preserve

AP (July 31, 2014) — Seacrest Wolf Preserve on the northern Florida panhandle allows more than 10,000 visitors each year to get up close and personal with Arctic and British Columbian Wolves. (July 31) Video provided by AP
Powered by NewsLook.com
Florida Panther Rebound Upsets Ranchers

Florida Panther Rebound Upsets Ranchers

AP (July 31, 2014) — With Florida's panther population rebounding, some ranchers complain the protected predators are once again killing their calves. (July 31) Video provided by AP
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) — Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Raw: Thousands Flocking to German Crop Circle

Raw: Thousands Flocking to German Crop Circle

AP (July 30, 2014) — Thousands of people are trekking to a Bavarian farmer's field to check out a mysterious set of crop circles. (July 30) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



      Save/Print:
      Share:  

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile iPhone Android Web
      Follow Facebook Twitter Google+
      Subscribe RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins