Featured Research

from universities, journals, and other organizations

Fly Larvae Shun The Light

Date:
June 29, 2009
Source:
BioMed Central
Summary:
Drosophila larvae avoid light during the foraging stage of their development. New research shows that both 5-HT (serotonergic) and corazonergic neurons have a role in regulating this behavior.

Drosophila larvae avoid light during the foraging stage of their development. New research shows that both 5-HT (serotonergic) and corazonergic neurons have a role in regulating this behavior.

To identify which neurons modulate the larvae's photobehavior, Verσnica G. Rodriguez Moncalvo and Ana Regina Campos from McMaster University, Ontario, Canada analysed Drosophila larvae which had been genetically engineered to achieve suppressed synaptic transmission in candidate neurons. Muted synaptic transmission can be achieved by targeted expression of tetanus toxin light chain (TNT), as when made in neurons TNT suppresses evoked and spontaneous neurotransmitter release.

The authors looked first at larvae in which dopaminergic, serotonergic and corazonergic neurons had been silenced by using the DOPA decarboxylase (Ddc) promoter to drive TNT expression, and subsequently at larvae expressing constructs with more specific promoters, in which different subsets of Ddc neurons were muted. Larvae with and without the function of these neurons were put through their paces in light and dark conditions.

The results show that inactivation of Ddc neurons increases the aversion to light, both during the foraging phase, when larvae are characteristically photophobic, and the later stages of development, when larvae are usually photoneutral. Both 5-HT neurons and corazonergic neurons, but not dopaminergic neurons, contribute to light-controlled larval locomotion, and this is modulated at least partly by 5-HT neurons located in the brain hemispheres. However, this modulation does not appear to occur at the photoreceptor level and may be mediated by 5-HT1ADro receptors. These findings may provide clues to help identify the target neurons of the serotonin signalling, which the authors believe could be critical for light-controlled movement.

"These findings provide new insights into the function of 5-HT neurons in Drosophila larval behavior, as well as into the mechanisms underlying regulation of larval response to light," says Campos.


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Veronica G Rodriguez Moncalvo and Ana REGINA Campos. Role of serotonergic neurons in the Drosophila larval response to light. BMC Neuroscience, (in press) [link]

Cite This Page:

BioMed Central. "Fly Larvae Shun The Light." ScienceDaily. ScienceDaily, 29 June 2009. <www.sciencedaily.com/releases/2009/06/090622192236.htm>.
BioMed Central. (2009, June 29). Fly Larvae Shun The Light. ScienceDaily. Retrieved August 27, 2014 from www.sciencedaily.com/releases/2009/06/090622192236.htm
BioMed Central. "Fly Larvae Shun The Light." ScienceDaily. www.sciencedaily.com/releases/2009/06/090622192236.htm (accessed August 27, 2014).

Share This




More Plants & Animals News

Wednesday, August 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Raw: Firefighters Rescue Puppy Stuck in Tire

Raw: Firefighters Rescue Puppy Stuck in Tire

AP (Aug. 26, 2014) — It took Houston firefighters more than an hour to free a puppy who got its head stuck in a tire. (Aug. 26) Video provided by AP
Powered by NewsLook.com
Have You Ever Been 'Sleep Drunk?' 1 in 7 Has

Have You Ever Been 'Sleep Drunk?' 1 in 7 Has

Newsy (Aug. 26, 2014) — A study published in the journal "Neurology" interviewed more than 19,000 people and found 15 percent suffer from being "sleep drunk." Video provided by Newsy
Powered by NewsLook.com
Great White Shark Spotted Off Massachusetts Coast

Great White Shark Spotted Off Massachusetts Coast

Reuters - US Online Video (Aug. 26, 2014) — A great white shark is spotted off the shore at Duxbury beach in Massachusetts forcing beach goers out of the water. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Raw: Elk Wanders Into German Office Building

Raw: Elk Wanders Into German Office Building

AP (Aug. 25, 2014) — A young bull elk wandered inside the office building of a company in Dresden, Germany on Monday. The elk became trapped between a wall and glass windows while rescue workers tried to rescue him safely. (Aug. 25) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



    Save/Print:
    Share:  

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile iPhone Android Web
    Follow Facebook Twitter Google+
    Subscribe RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins