Featured Research

from universities, journals, and other organizations

Common Antibacterial Treatment Linked To Sensorineural Hearing Loss In Cystic Fibrosis Patients

Date:
July 1, 2009
Source:
American Academy of Otolaryngology -- Head and Neck Surgery
Summary:
An otherwise effective treatment for cystic fibrosis places patients at a high risk of sensorineural hearing loss, according to new research.

An otherwise effective treatment for cystic fibrosis places patients at a high risk of sensorineural hearing loss, according to new research published in the July edition of Otolaryngology-Head and Neck Surgery.

Related Articles


Cystic fibrosis is an inherited chronic disease that affects the lungs and digestive system of about 30,000 children and adults in the United States (70,000 worldwide). A defective gene and its protein product cause the body to produce unusually thick, sticky mucus that clogs the lungs and leads to life-threatening lung infections; and obstructs the pancreas and stops natural enzymes from helping the body break down and absorb food.

Researchers reviewed the medical records of cystic fibrosis (CF) patients at Children's Hospital Boston over a 13 year period, and found that seven of 50 CF patients (14%) suffered from sensorineural hearing loss. Of that group, 43 percent of those that had received aminoglycosides intravenously had received more than 10 courses of the treatment; patients who were treated more than five times with nasal irrigation of aminoglycosides were also at risk of sensorineural hearing loss.

Because CF patients are prone to suffer from infections of the pulmonary and sinonasal systems, aminoglycosides are commonly administered to CF patients because of the potent effect they have on bacteria. The treatment is considered so effective that it outweighs the well-known side-effects, which include hair cell loss, and thus hearing loss.

The authors contend that CF patients should have routine hearing evaluations that specifically target the detection of sensorineural hearing loss, especially when repeated courses of systemic or intranasal aminoglycosides have be used in treatment. They also note that further investigation through a prospective study is warranted in order to replicate these results.

The study's authors are Alan G. Cheng, MD; Patrick R. Johnston, MMath; Jeniffer Luz, BS; Ahmet Uluer, DO; Brian Fligor, ScD; Greg R. Licameli, MD, MHCM; Margaret A. Kenna, MD, MPH; and Dwight T. Jones, MD.


Story Source:

The above story is based on materials provided by American Academy of Otolaryngology -- Head and Neck Surgery. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Otolaryngology -- Head and Neck Surgery. "Common Antibacterial Treatment Linked To Sensorineural Hearing Loss In Cystic Fibrosis Patients." ScienceDaily. ScienceDaily, 1 July 2009. <www.sciencedaily.com/releases/2009/07/090701082704.htm>.
American Academy of Otolaryngology -- Head and Neck Surgery. (2009, July 1). Common Antibacterial Treatment Linked To Sensorineural Hearing Loss In Cystic Fibrosis Patients. ScienceDaily. Retrieved April 18, 2015 from www.sciencedaily.com/releases/2009/07/090701082704.htm
American Academy of Otolaryngology -- Head and Neck Surgery. "Common Antibacterial Treatment Linked To Sensorineural Hearing Loss In Cystic Fibrosis Patients." ScienceDaily. www.sciencedaily.com/releases/2009/07/090701082704.htm (accessed April 18, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, April 18, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Our Love Of Puppy Dog Eyes Explained By Science

Our Love Of Puppy Dog Eyes Explained By Science

Newsy (Apr. 17, 2015) Researchers found a spike in oxytocin occurs in both humans and dogs when they gaze into each other&apos;s eyes. Video provided by Newsy
Powered by NewsLook.com
Scientists Find Link Between Gestational Diabetes And Autism

Scientists Find Link Between Gestational Diabetes And Autism

Newsy (Apr. 17, 2015) Researchers who analyzed data from over 300,000 kids and their mothers say they&apos;ve found a link between gestational diabetes and autism. Video provided by Newsy
Powered by NewsLook.com
Video Messages Help Reassure Dementia Patients

Video Messages Help Reassure Dementia Patients

AP (Apr. 17, 2015) Family members are prerecording messages as part of a unique pilot program at the Hebrew Home in New York. The videos are trying to help victims of Alzheimer&apos;s disease and other forms of dementia break through the morning fog of forgetfulness. (April 17) Video provided by AP
Powered by NewsLook.com
Boy or Girl? Intersex Awareness Is on the Rise

Boy or Girl? Intersex Awareness Is on the Rise

AP (Apr. 17, 2015) At least 1 in 5,000 U.S. babies are born each year with intersex conditions _ ambiguous genitals because of genetic glitches or hormone problems. Secrecy and surgery are common. But some doctors and activists are trying to change things. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins