Featured Research

from universities, journals, and other organizations

Effective Treatment For Infective Endocarditis Using A Rigorous Hospital Management-based Approach

Date:
August 7, 2009
Source:
CNRS (Délégation Paris Michel-Ange)
Summary:
A clinical study has demonstrated that a standardized management protocol for patients with infective endocarditis can dramatically reduce mortality rates. In 2002, a simple, rigorous and standardized protocol for therapeutic management were introduced by the team. The results were eloquent: mortality rates were divided by three during the hospitalization of patients.

A clinical study carried out at Hôpital de la Timone in Marseille has demonstrated that a standardized management protocol for patients with infective endocarditis can dramatically reduce mortality rates.

In 2002, a simple, rigorous and standardized protocol for therapeutic management were introduced by the team led by Didier Raoult from the Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (Université Aix Marseille 2/CNRS). The results were eloquent: mortality rates were divided by three during the hospitalization of patients. This study was the subject of a publication in the Archive of Internal Medicine.

Infective endocarditis is a serious condition that affects nearly 2000 people each year in France, a quarter of whom will die. This infection is usually of bacterial origin, and affects the heart tissues or implanted medical devices such as prostheses, pacemakers or defibrillators. In around 50% of cases, treatment for this condition includes a surgical procedure. Despite advances in the therapeutic resources available, mortality rates associated with this disease have not diminished for many years.

Because international therapeutic guidelines differ from one continent to another, and because of the large number of medical specialties involved, the management of patients can vary considerably. For this reason, in 2002, Didier Raoult from URMITE (Université Aix Marseille 2/CNRS) set up a multidisciplinary medical team comprising cardiologists, specialists in infectious diseases and heart surgeons at the Hôpital de la Timone. They drew up a consensus protocol for the specific management of infective endocarditis. Rigorous, precise and simple, this protocol was designed to standardize diagnostic and therapeutic methods and practices that could be applied at a very broad scale. For example, prescriptions were restricted to only four types of antibiotic, and surgical indications - as well as their degree of urgency - were very clearly defined.

During this clinical study, the vital prognosis of 333 patients, treated using this protocol or not, was monitored. Thanks to this new, standardized management, the mortality rates observed during hospitalization fell from 12.7% to 4.4%, and mortality at 1 year from 18.5% to 8.2%. These mortality rates, the lowest ever published, reinforce the conviction that the multidisciplinary but standardized management of a disease as severe as infective endocarditis is crucial to therapeutic success.

 


Story Source:

The above story is based on materials provided by CNRS (Délégation Paris Michel-Ange). Note: Materials may be edited for content and length.


Cite This Page:

CNRS (Délégation Paris Michel-Ange). "Effective Treatment For Infective Endocarditis Using A Rigorous Hospital Management-based Approach." ScienceDaily. ScienceDaily, 7 August 2009. <www.sciencedaily.com/releases/2009/08/090807120051.htm>.
CNRS (Délégation Paris Michel-Ange). (2009, August 7). Effective Treatment For Infective Endocarditis Using A Rigorous Hospital Management-based Approach. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2009/08/090807120051.htm
CNRS (Délégation Paris Michel-Ange). "Effective Treatment For Infective Endocarditis Using A Rigorous Hospital Management-based Approach." ScienceDaily. www.sciencedaily.com/releases/2009/08/090807120051.htm (accessed April 18, 2014).

Share This



More Health & Medicine News

Friday, April 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) — President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com
Is Apathy A Sign Of A Shrinking Brain?

Is Apathy A Sign Of A Shrinking Brain?

Newsy (Apr. 17, 2014) — A recent study links apathetic feelings to a smaller brain. Researchers say the results indicate a need for apathy screening for at-risk seniors. Video provided by Newsy
Powered by NewsLook.com
Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) — A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com
Thousands Of Vials Of SARS Virus Go Missing

Thousands Of Vials Of SARS Virus Go Missing

Newsy (Apr. 16, 2014) — A research institute in Paris somehow misplaced more than 2,000 vials of the deadly SARS virus. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins