Kudzu, the nuisance vine that has overgrown almost 10 million acres in the southeastern United States, may sprout into a dietary supplement. Scientists in Alabama and Iowa are reporting the first evidence that root extracts from kudzu show promise as a dietary supplement for a high-risk condition — the metabolic syndrome — that affects almost 50 million people in the United States alone.
An excessive amount of glucose in the blood is linked to both diabetes and obesity. Wyss says puerarin seems to regulate glucose by steering it to places where it is beneficial, such as muscles, and away from fat cells and blood vessels.
J. Michael Wyss and colleagues note in the new study that people with metabolic syndrome have obesity, high blood pressure, high blood cholesterol, and problems with their body's ability to use insulin. Those disorders mean a high risk for heart attacks, strokes, and other diseases. Scientists have been seeking natural substances that can treat the metabolic syndrome. The new study evaluated kudzu root extracts, which contain healthful substances called isoflavones. People in China and Japan long have used kudzu supplements as a health food.
The study found that a kudzu root extract had beneficial effects lab rats used as a model for research on the metabolic syndrome. After two months of taking the extract, the rats had lower cholesterol, blood pressure, blood sugar, and insulin levels that a control group not given the extract. Kudzu root "may provide a dietary supplement that significantly decreases the risk and severity of stroke and cardiovascular disease in at-risk individuals," the article notes.
- Peng et al. Chronic Dietary Kudzu Isoflavones Improve Components of Metabolic Syndrome in Stroke-Prone Spontaneously Hypertensive Rats. Journal of Agricultural and Food Chemistry, 2009; 57 (16): 7268 DOI: 10.1021/jf901169y
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