Featured Research

from universities, journals, and other organizations

Relationship Between Androgen Deficiency And Cardiovascular Disease Proposed

Date:
September 28, 2009
Source:
Boston University Medical Center
Summary:
Researchers believe that androgen deficiency might be the underlying cause for a variety of common clinical conditions, including diabetes, erectile dysfunction, metabolic syndrome and cardiovascular disease.

Researchers from Boston University School of Medicine (BUSM) in collaboration with researchers from Lahey Clinic Northshore, Peabody, Mass., believe that androgen deficiency might be the underlying cause for a variety of common clinical conditions, including diabetes, erectile dysfunction, metabolic syndrome and cardiovascular disease (CVD).

These findings appear in the September/October issue of the Journal of Andrology.

Androgens are a steroid hormone, such as testosterone, that controls the development and maintenance of male characteristics. In a number of studies, androgen deficiency has been linked to an increased mortality in men. Testosterone (T) is an anabolic hormone with a wide range of beneficial effects on men's health. However, according to the BUSM researchers, the therapeutic role of T in men's health remains a hotly debated issue for a number of reasons, including the purported risk of prostate cancer.

To evaluate the relationships between T deficiency and risk factors of CVD and to determine the implications of androgen deficiency in men with cardiovascular risk factors, the researchers performed a comprehensive literature search with the use of PubMed from 1980 through 2008. Relevant articles pertinent to androgen deficiency and vascular disease were evaluated and it was determined that a relationship did exist between androgen deficiency and CVD.

"In view of the emerging evidence suggesting that androgen deficiency is a risk factor for CVD, androgen replacement therapy could potentially reduce CVD risk in hypogonadal men. It should be emphasized, however, that androgen replacement therapy should be done with very thorough and careful monitoring for prostate diseases," said lead author Abdulmaged M. Traish, MBA, PhD, a professor of biochemistry and urology as well as the director of Laboratories for Sexual Medicine, Institute for Sexual Medicine at BUSM.

To further elucidate the role of androgen deficiency in vascular disease, the researchers recommend large, long-term, double-blind, randomized, placebo-controlled clinical trials be carried out. "Although challenges might lie ahead regarding how data from such clinical trials are to be properly interpreted and whether long-term safety can be established with T supplementation, these findings warrant definite investigation into the beneficial role that androgens might have in preventing cardiovascular risk in androgen-deficient men," added Traish.


Story Source:

The above story is based on materials provided by Boston University Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

Boston University Medical Center. "Relationship Between Androgen Deficiency And Cardiovascular Disease Proposed." ScienceDaily. ScienceDaily, 28 September 2009. <www.sciencedaily.com/releases/2009/09/090927130034.htm>.
Boston University Medical Center. (2009, September 28). Relationship Between Androgen Deficiency And Cardiovascular Disease Proposed. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2009/09/090927130034.htm
Boston University Medical Center. "Relationship Between Androgen Deficiency And Cardiovascular Disease Proposed." ScienceDaily. www.sciencedaily.com/releases/2009/09/090927130034.htm (accessed October 21, 2014).

Share This



More Health & Medicine News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC Revamps Ebola Guidelines After Criticism

CDC Revamps Ebola Guidelines After Criticism

Newsy (Oct. 21, 2014) The Centers for Disease Control and Prevention have issued new protocols for healthcare workers interacting with Ebola patients. Video provided by Newsy
Powered by NewsLook.com
First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com
CDC Issues New Ebola Guidelines for Health Workers

CDC Issues New Ebola Guidelines for Health Workers

Reuters - US Online Video (Oct. 21, 2014) The U.S. Centers for Disease Control and Prevention has set up new guidelines for health workers taking care of patients infected with Ebola. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
'Cadaver Dog' Sniffs out Human Remains

'Cadaver Dog' Sniffs out Human Remains

AP (Oct. 21, 2014) Where's a body buried? Buster's nose can often tell you. He's a cadaver dog, specially trained to find human remains and increasingly being used by law enforcement and accepted in courts. These dogs are helping solve even decades-old mysteries. (Oct. 21) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins