Featured Research

from universities, journals, and other organizations

Statins May Prevent Blood Clots In Patients With Cardiovascular Disease

Date:
November 5, 2009
Source:
American College of Chest Physicians
Summary:
New research shows that patients with atherosclerosis receiving statin therapy had a significantly reduced risk of developing venous thromboembolism -- a collective term for DVT (blood clot) and pulmonary embolism -- than patients not on statin therapy.

Statins may provide potentially life-saving benefits for patients with cardiovascular disease by helping reduce the incidence of blood clots.

Related Articles


New research presented at CHEST 2009, the 75th annual international scientific assembly of the American College of Chest Physicians (ACCP), shows that patients with atherosclerosis receiving statin therapy had a significantly reduced risk of developing venous thromboembolism (VTE) -- a collective term for DVT (blood clot) and pulmonary embolism (PE) -- than patients not on statin therapy. Furthermore, patients on a higher dose of statins had the least likelihood of developing VTE.

"Research has indicated an association between atherosclerosis and venous thrombosis," said lead author Danai Khemasuwan, MD, Albert Einstein Medical Center, Philadelphia, PA. "However, in our study, statin therapy demonstrated a protective effect on this group of patients, reducing their overall incidence of developing VTE."

To investigate the association between statin use and incidence of VTE, researchers from Albert Einstein Medical Center reviewed the cases of 593 patients (mean age, 67.8 years) who were admitted to the hospital for myocardial infarction or ischemic stroke. Of the patients, 73 percent (N=433) were receiving statins, and the overall incidence of VTE was 13 percent (N=77).

Results of the analysis showed that patients in the nonstatin group were three times as likely to develop VTE than patients receiving statins, 26.3 percent vs. 8.3 percent, respectively. Even after controlling for factors related to VTE (smoking, history of cancer, and immobilization), statins use was still associated with a low risk of developing VTE. Furthermore, patients receiving high-dose statins (greater than 40 mg/day) showed a lower occurrence of VTE compared with patients receiving standard dose statins, suggesting a dose-related response between statins and VTE.

VTE is a potentially life-threatening condition that occurs in more than 2 million Americans each year. Patients most at risk for VTE are those with cancer, those who have recently had surgery, and patients who have experience acute trauma. Although the current analysis only included patients with atherosclerosis, previous research by Dr. Khemasuwan showed that statins had a similar effect on patients with cancer. The authors caution that it is still too early to speculate the effect that statins may have on other high-risk groups, like surgical patients.

"Venous thromboembolism leads to significant morbidity, mortality, and hospital costs in Americans each year," said Kalpalatha Guntupalli, MD, FCCP, President of the American College of Chest Physicians. "Although more research is needed, statins may prove effective in helping to reduce the incidence of VTE in specific patient populations."


Story Source:

The above story is based on materials provided by American College of Chest Physicians. Note: Materials may be edited for content and length.


Cite This Page:

American College of Chest Physicians. "Statins May Prevent Blood Clots In Patients With Cardiovascular Disease." ScienceDaily. ScienceDaily, 5 November 2009. <www.sciencedaily.com/releases/2009/11/091103144812.htm>.
American College of Chest Physicians. (2009, November 5). Statins May Prevent Blood Clots In Patients With Cardiovascular Disease. ScienceDaily. Retrieved November 21, 2014 from www.sciencedaily.com/releases/2009/11/091103144812.htm
American College of Chest Physicians. "Statins May Prevent Blood Clots In Patients With Cardiovascular Disease." ScienceDaily. www.sciencedaily.com/releases/2009/11/091103144812.htm (accessed November 21, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

UN Says It Will Scale Up Its Ebola Response

UN Says It Will Scale Up Its Ebola Response

AFP (Nov. 20, 2014) UN Resident Coordinator David McLachlan-Karr and WHO representative in the country Daniel Kertesz updated the media on the UN Ebola response on Wednesday. Duration: 00:51 Video provided by AFP
Powered by NewsLook.com
Takata Offers "sincerest Condolences" To Victims of Malfunctioning Airbag

Takata Offers "sincerest Condolences" To Victims of Malfunctioning Airbag

Reuters - US Online Video (Nov. 20, 2014) U.S. Congress hears from a victim and company officials as it holds a hearing on the safety of Takata airbags after reports of injuries. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Obesity Costs Almost As Much As War And Terrorism

Obesity Costs Almost As Much As War And Terrorism

Newsy (Nov. 20, 2014) The newest estimate of the cost of obesity is pretty jarring — $2 trillion. But how did researchers get to that number? Video provided by Newsy
Powered by NewsLook.com
Calling All Men: Here's Your Chance to Experience Labor Pains

Calling All Men: Here's Your Chance to Experience Labor Pains

Reuters - Light News Video Online (Nov. 20, 2014) Chinese hospital offers men a chance to experience the pain of child birth via electric shocks. Sharon Reich reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins