Featured Research

from universities, journals, and other organizations

Folic Acid Supplements Linked To Asthma, Study Suggests

Date:
November 4, 2009
Source:
University of Adelaide
Summary:
A new study may have shed light on the rise in childhood asthma in developed countries like Australia in recent decades. Researchers have identified a link between folic acid supplements taken in late pregnancy and allergic asthma in children aged between 3 and 5 years, suggesting that the timing of supplementation in pregnancy is important.

A University of Adelaide study may have shed light on the rise in childhood asthma in developed countries like Australia in recent decades.

Related Articles


Researchers from the University's Robinson Institute have identified a link between folic acid supplements taken in late pregnancy and allergic asthma in children aged between 3 and 5 years, suggesting that the timing of supplementation in pregnancy is important.

Associate Professor Michael Davies says that folic acid supplements -- recommended for pregnant women to prevent birth defects -- appear to have "additional and unexpected" consequences in recent studies in mice and infants.

"In our study, supplemental folic acid in late pregnancy was associated with an increased risk of asthma in children, but there was no evidence to suggest any adverse effects if supplements were taken in early pregnancy."

The University of Adelaide findings have been published in the American Journal of Epidemiology.

The study involved more than 500 women whose maternal diet and supplements were assessed twice during their pregnancy, with follow-up on their child's asthma status at 3.5 years and 5.5 years. Asthma was reported in 11.6% of children at 3.5 years and 11.8% of children at 5.5 years. Nearly a third of these children reported persistent asthma.

Current public health guidelines recommend that women consume a supplemental dose of 400 micrograms of folic acid per day in the month preceding and during the first trimester of pregnancy to reduce the risk of neural tube defects in children.

"Our study supports these guidelines, as we found no increased risk of asthma if folic acid supplements were taken in pre or early pregnancy," Associate Professor Davies says. However, these guidelines may need to be expanded to include recommendations about avoiding use of high dose supplemental folic acid in late pregnancy."

He says their study found no evidence to link asthma with dietary folate, which is found in green, leafy vegetables, certain fruits and nuts.

Nearly half of all mothers in the study took a folic acid supplement pre-pregnancy and 56% met the required daily dosage of 400 micrograms in early pregnancy.

"These findings show there is a potentially important critical period during which folic acid supplement dosages may be manipulated to optimise their neuro-protective effects while not increasing the risk of asthma," Associate Professor Davies says.


Story Source:

The above story is based on materials provided by University of Adelaide. Note: Materials may be edited for content and length.


Cite This Page:

University of Adelaide. "Folic Acid Supplements Linked To Asthma, Study Suggests." ScienceDaily. ScienceDaily, 4 November 2009. <www.sciencedaily.com/releases/2009/11/091104111735.htm>.
University of Adelaide. (2009, November 4). Folic Acid Supplements Linked To Asthma, Study Suggests. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2009/11/091104111735.htm
University of Adelaide. "Folic Acid Supplements Linked To Asthma, Study Suggests." ScienceDaily. www.sciencedaily.com/releases/2009/11/091104111735.htm (accessed October 24, 2014).

Share This



More Health & Medicine News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins