Featured Research

from universities, journals, and other organizations

How to divide and conquer 'social network' of cells

Date:
January 11, 2010
Source:
University of Montreal
Summary:
On Noah's Ark animals came in twos: male and female. In human bodies trillions of cells are coupled, too, and so are the molecules from which they are composed. Yet these don't come in twos, they are regrouped into indistinguishable clusters. Because these complex cell networks are the backbone of life -- and illness -- scientists have long searched for ways to splice cell clusters down to their original pairs.

On Noah's Ark animals came in twos: male and female. In human bodies trillions of cells are coupled, too, and so are the molecules from which they are composed. Yet these don't come in twos, they are regrouped into indistinguishable clusters. Because these complex cell networks are the backbone of life -- and illness -- scientists have long searched for ways to splice cell clusters down to their original pairs.

Related Articles


According to a new study in the journal Nature Methods, Université de Montréal scientists Stephen Michnick and Po Hien Ear have managed the feat of dividing cell networks down to their genesis. The discovery could have applications for diseases such as cancer, where blood-thirsty cells could be decoupled to curb their multiplication in the human body.

"We have provided a simple way to decouple one cellular network from another," says Dr. Michnick, a Université de Montréal biochemistry professor and Canada Research Chair in Integrative Genomics. "Once decoupled, we could clearly distinguish what one network was doing versus another."

As part of their study, the researchers reproduced gene networks using baker's yeast -- a cellular organism proven to resemble the critical functions of human cells. "We cut out relationships between cells to see which are crucial and which are not," explains Dr. Michnick. "We found that de-coupling cells permitted growth regulation. One way to attack cancer would be to find molecules that decouple other networks (as we did), slow down its growth and weaken the illness."


Story Source:

The above story is based on materials provided by University of Montreal. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ear et al. A general life-death selection strategy for dissecting protein functions. Nature Methods, 2009; 6 (11): 813 DOI: 10.1038/nmeth.1389

Cite This Page:

University of Montreal. "How to divide and conquer 'social network' of cells." ScienceDaily. ScienceDaily, 11 January 2010. <www.sciencedaily.com/releases/2009/11/091109121211.htm>.
University of Montreal. (2010, January 11). How to divide and conquer 'social network' of cells. ScienceDaily. Retrieved December 19, 2014 from www.sciencedaily.com/releases/2009/11/091109121211.htm
University of Montreal. "How to divide and conquer 'social network' of cells." ScienceDaily. www.sciencedaily.com/releases/2009/11/091109121211.htm (accessed December 19, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, December 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) — It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) — More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) — In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Buzz60 (Dec. 19, 2014) — A double-amputee makes history by becoming the first person to wear and operate two prosthetic arms using only his mind. Jen Markham has the story. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins