Featured Research

from universities, journals, and other organizations

Secondhand smoke exposure in childhood increases lung cancer risk later in life

Date:
December 4, 2009
Source:
American Association for Cancer Research
Summary:
Children exposed to secondhand cigarette smoke have an increased risk of developing lung cancer in adulthood, even if they never smoked.

Children exposed to secondhand cigarette smoke have an increased risk of developing lung cancer in adulthood, even if they never smoked.

Related Articles


Results of this study are published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research, as part of a special tobacco focus in the December issue.

This year alone, more than 219,000 Americans will be diagnosed with lung cancer; more than 159,000 will die from it and some of those may be people who have never smoked. Studies to date have shown that exposure to secondhand smoke in adulthood has detrimental health effects, but data are limited on one's risk of developing lung cancer when exposed as a child.

What makes this study different from previous research is that it was conducted in two independent cohorts and included a molecular analysis of gene variants of innate immunity -- the mannose binding lection-2 gene, or MBL2 gene. The MBL2 gene is known to affect susceptibility to respiratory diseases.

Using the ongoing National Cancer Institute-Maryland Lung Cancer study (624 cases; 348 controls), Curtis C. Harris, M.D., chief of the Laboratory of Human Carcinogenesis at NCI, and colleagues collected information on secondhand smoke history among men and women. They used DNA for genotyping the MBL2 gene. Then, to compare, Harris, Ping Yang, M.D., Ph.D., professor of epidemiology at the Mayo Clinic in Rochester, Minn., and colleagues used results from a Mayo Clinic study (461 never smokers; 172 cases; 289 controls).

Harris and colleagues found an association between childhood exposure to secondhand tobacco smoke and increased risk of lung cancer in adulthood. Furthermore, MBL2 activity was associated with an even more increased risk among those who were exposed to secondhand smoke in childhood.

Based on the results of this study, Harris said "children should not be exposed to secondhand tobacco smoke due to the long-term health implications they can face in adulthood." He added that these results warrant further investigation in a larger study population.


Story Source:

The above story is based on materials provided by American Association for Cancer Research. Note: Materials may be edited for content and length.


Cite This Page:

American Association for Cancer Research. "Secondhand smoke exposure in childhood increases lung cancer risk later in life." ScienceDaily. ScienceDaily, 4 December 2009. <www.sciencedaily.com/releases/2009/12/091203090059.htm>.
American Association for Cancer Research. (2009, December 4). Secondhand smoke exposure in childhood increases lung cancer risk later in life. ScienceDaily. Retrieved January 25, 2015 from www.sciencedaily.com/releases/2009/12/091203090059.htm
American Association for Cancer Research. "Secondhand smoke exposure in childhood increases lung cancer risk later in life." ScienceDaily. www.sciencedaily.com/releases/2009/12/091203090059.htm (accessed January 25, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, January 25, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Mistakes Should Serve a Lesson Says WHO

Ebola Mistakes Should Serve a Lesson Says WHO

AFP (Jan. 25, 2015) The World Health Organization&apos;s chief on Sunday admitted the UN agency had been caught napping on Ebola, saying it should serve a lesson to avoid similar mistakes in future. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
Disneyland Measles Outbreak Spreads To 5 States

Disneyland Measles Outbreak Spreads To 5 States

Newsy (Jan. 24, 2015) Much of the Disneyland measles outbreak is being blamed on the anti-vaccination movement. The CDC encourages just about everyone get immunized. Video provided by Newsy
Powered by NewsLook.com
Growing Measles Outbreak Worries Calif. Parents

Growing Measles Outbreak Worries Calif. Parents

AP (Jan. 23, 2015) Public health officials are rushing to contain a measles outbreak that has sickened 70 people across 6 states and Mexico. The AP&apos;s Raquel Maria Dillon has more. (Jan. 23) Video provided by AP
Powered by NewsLook.com
Smart Wristband to Shock Away Bad Habits

Smart Wristband to Shock Away Bad Habits

Reuters - Innovations Video Online (Jan. 23, 2015) A Boston start-up is developing a wristband they say will help users break bad habits by jolting them with an electric shock. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins