Featured Research

from universities, journals, and other organizations

How gene action may lead to diabetes prevention, cure

Date:
December 14, 2009
Source:
Texas A&M AgriLife Communications
Summary:
A gene commonly studied by cancer researchers has been linked to the metabolic inflammation that leads to diabetes. Understanding how the gene works means scientists may be closer to finding ways to prevent or cure diabetes.

A gene commonly studied by cancer researchers has been linked to the metabolic inflammation that leads to diabetes.

Understanding how the gene works means scientists may be closer to finding ways to prevent or cure diabetes, according to a study by Texas AgriLife Research appearing in the Journal of Biological Chemistry.

"Because we understand the mechanism, or how the gene works, we believe a focus on nutrition will find the way to both prevent and reverse diabetes," said Dr. Chaodong Wu, AgriLife Research nutrition and food scientist who authored the paper with the University of Minnesota's Dr. Yuqing Hou.

Wu said the research team will collaborate with nutritionists to identify what changes or supplements in a diet will activate the gene to prevent or stop the progression of diabetes.

Diabetes is a disease in which blood sugar (glucose) levels are higher than normal and the body has a hard time converting food to glucose which is then turned into energy, according to the National Institutes of Health. When the body cannot metabolize food, the amount of glucose builds in the blood while the cells lack energy. Complications can include heart disease, stroke, kidney disease, blindness, nerve problems and gum infections. Some of the complications can lead to amputation.

The gene with the possible answers to ways of fighting the disease is known in the science world as PFKFB3. Wu and the team of researchers identified it as a regulator for metabolism, which plays a vital role in the development of diabetes.

Wu noted that while it is a major health concern in the U.S., obesity does not necessarily cause diabetes to develop; i.e., just because a person is overweight does not mean they have diabetes. Rather, "metabolic inflammation" causes or exacerbates the disease. That's where the team began looking at PFKFB3 -- because it regulates metabolism -- to find the mechanism or how the inflammation begins. Metabolic inflammation is different from classic inflammation because there is no infection, virus or bacteria present, though the symptoms appear similar.

He believes nutritionists working with the biological chemists can help develop food consumption plans that either prevent people from developing metabolic inflammation or cause existing conditions to retreat.

"First we will need to identify what effective compounds will trigger the gene to regulate metabolism," Wu said. "Then we need to determine what combinations within foods are more effective."

In the meantime, Wu suggested, people need to consume healthier foods.

"Basically, fish and seafood," Wu said. "That's always good in a diet."


Story Source:

The above story is based on materials provided by Texas A&M AgriLife Communications. Note: Materials may be edited for content and length.


Cite This Page:

Texas A&M AgriLife Communications. "How gene action may lead to diabetes prevention, cure." ScienceDaily. ScienceDaily, 14 December 2009. <www.sciencedaily.com/releases/2009/12/091211200343.htm>.
Texas A&M AgriLife Communications. (2009, December 14). How gene action may lead to diabetes prevention, cure. ScienceDaily. Retrieved September 1, 2014 from www.sciencedaily.com/releases/2009/12/091211200343.htm
Texas A&M AgriLife Communications. "How gene action may lead to diabetes prevention, cure." ScienceDaily. www.sciencedaily.com/releases/2009/12/091211200343.htm (accessed September 1, 2014).

Share This




More Health & Medicine News

Monday, September 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

We've Got Mites Living In Our Faces And So Do You

We've Got Mites Living In Our Faces And So Do You

Newsy (Aug. 30, 2014) A new study suggests 100 percent of adult humans (those over 18 years of age) have Demodex mites living in their faces. Video provided by Newsy
Powered by NewsLook.com
Liberia Continues Fight Against Ebola

Liberia Continues Fight Against Ebola

AFP (Aug. 30, 2014) Authorities in Liberia try to stem the spread of the Ebola epidemic by raising awareness and setting up sanitation units for people to wash their hands. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com
California Passes 'yes-Means-Yes' Campus Sexual Assault Bill

California Passes 'yes-Means-Yes' Campus Sexual Assault Bill

Reuters - US Online Video (Aug. 30, 2014) California lawmakers pass a bill requiring universities to adopt "affirmative consent" language in their definitions of consensual sex, part of a nationwide drive to curb sexual assault on campuses. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
New Drug Could Reduce Cardiovascular Deaths

New Drug Could Reduce Cardiovascular Deaths

Newsy (Aug. 30, 2014) The new drug from Novartis could reduce cardiovascular deaths by 20 percent compared to other similar drugs. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins