Featured Research

from universities, journals, and other organizations

Ultrasound measurement of fetal adrenal gland a better predictor of preterm birth

Date:
February 19, 2010
Source:
Society for Maternal-Fetal Medicine
Summary:
Researchers have shown that measuring the fetal zone of the adrenal gland is a better predictor of pre-term birth than measuring cervical length.

In a study to be presented February 4 at the Society for Maternal-Fetal Medicine's (SMFM) annual meeting, The Pregnancy Meeting ™, in Chicago, researchers will unveil findings that show that measuring the fetal zone of the adrenal gland is a better predictor of pre-term birth than measuring cervical length.

Researchers with the University of Maryland and Yale University have followed up on early research that they conducted using 3D ultrasound methods.

"We previously discovered that 3D adrenal gland volume (AGV) is a very accurate predictor of preterm birth," said Dr. Ozhan Turan, the study's author. "However most people around the world don't have access to that technology, therefore, we have created measurements that can be done with 2D ultrasound that are very effective to predict pre-term birth."

In the study, patients presenting with preterm labor symptoms had ultrasound measurement of the cervical length (CL) and fetal adrenal gland dimension. Using 3D ultrasound with VOCAL cAGV (AGV/ Estimated fetal weight), 2D depth of the whole-gland (D) and fetal zone (d) were measured. The d/D ratio was calculated as an index of FZE. The cAGV, d/D and CL were compared for prediction of preterm birth within seven days.

Sixty-two singletons with preterm labor at 23-37 wks´ gestation were studied. Measurement-to-delivery interval only correlated with cAGV and d/D (r=-0.32 p=0.011 and r=-0.47 p=0.001respectively) but not CL (p=0.83). Twenty women had preterm birth at less than seven days (Group A) while 42 (Group B) delivered in seven days or more from initial assessment. While CL was similar (p=0.5) cAGV and d/D were higher in group A (p< 0.0001 for both). ROC area under the curve was significantly greater for cAGV and d/D than for CL (0.82, 0.91 and 0.59, p< 0.01 and 0.001 respectively, fig) without any significant differences between adrenal gland measurements. Using ROC derived cutoffs for preterm birth in less than seven days was best predicted by d/D and cAGV but not CL.

"Prior to this we haven't had a good method to predict who will present with pre-term labor." said Dr. Turan. "Measuring the cervical length leads to a high percentage of false positives and also it has limited sensitivity," he continued. "Hopefully, if adopted, this method will allow for an easy inexpensive way to identify real pre-term deliveries. Therefore we will be better managing these pregnancies."


Story Source:

The above story is based on materials provided by Society for Maternal-Fetal Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Society for Maternal-Fetal Medicine. "Ultrasound measurement of fetal adrenal gland a better predictor of preterm birth." ScienceDaily. ScienceDaily, 19 February 2010. <www.sciencedaily.com/releases/2010/02/100204075023.htm>.
Society for Maternal-Fetal Medicine. (2010, February 19). Ultrasound measurement of fetal adrenal gland a better predictor of preterm birth. ScienceDaily. Retrieved July 28, 2014 from www.sciencedaily.com/releases/2010/02/100204075023.htm
Society for Maternal-Fetal Medicine. "Ultrasound measurement of fetal adrenal gland a better predictor of preterm birth." ScienceDaily. www.sciencedaily.com/releases/2010/02/100204075023.htm (accessed July 28, 2014).

Share This




More Health & Medicine News

Monday, July 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Trees Could Save More Than 850 Lives Each Year

Trees Could Save More Than 850 Lives Each Year

Newsy (July 27, 2014) — A national study conducted by the USDA Forest Service found that trees collectively save more than 850 lives on an annual basis. Video provided by Newsy
Powered by NewsLook.com
Google's Next Frontier: The Human Body

Google's Next Frontier: The Human Body

Newsy (July 27, 2014) — Google is collecting genetic and molecular information to paint a picture of the perfectly healthy human. Video provided by Newsy
Powered by NewsLook.com
What's To Blame For Worst Ebola Outbreak In History?

What's To Blame For Worst Ebola Outbreak In History?

Newsy (July 27, 2014) — A U.S. doctor has tested positive for the deadly Ebola virus, as the worst-ever outbreak continues to grow. Video provided by Newsy
Powered by NewsLook.com
Losing Sleep Leaves You Vulnerable To 'False Memories'

Losing Sleep Leaves You Vulnerable To 'False Memories'

Newsy (July 27, 2014) — A new study shows sleep deprivation can make it harder for people to remember specific details of an event. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins