Featured Research

from universities, journals, and other organizations

Vertebroplasty: Integral to treating back pain in blood marrow cancer patients

Date:
March 15, 2010
Source:
Society of Interventional Radiology
Summary:
Treating non-osteoporotic compression fractures in patients with multiple myeloma, a blood cancer, shows that the use of vertebroplasty -- a minimally invasive treatment performed by interventional radiologists using imaging guidance that stabilizes collapsed vertebrae with the injection of medical-grade bone cement into the spine -- results in a reduction of pain, medication usage and disability, according to researchers in the largest study of its kind.

Treating non-osteoporotic compression fractures in patients with multiple myeloma, a blood cancer, shows that the use of vertebroplasty -- a minimally invasive treatment performed by interventional radiologists using imaging guidance that stabilizes collapsed vertebrae with the injection of medical-grade bone cement into the spine -- results in a reduction of pain, medication usage and disability, according to researchers in the largest study of its kind at the Society of Interventional Radiology's 35th Annual Scientific Meeting in Tampa, Fla.

"The minimally invasive, image-guided treatment of vertebroplasty is an integral component to the complicated treatment of multiple myeloma, an incurable (yet treatable) cancer of the bone marrow that causes destructive lesions in bones and makes them more susceptible to fracture. By reducing pain and improving mobility, vertebroplasty helps patients become better equipped to continue with their rigorous treatment for multiple myeloma," said Eren Erdem, M.D., associate professor of radiology and neurosurgery and chief of interventional neuroradiology at the University of Arkansas for Medical Sciences in Little Rock. "There are many studies reporting the effectiveness of vertebroplasty in treating osteoporotic vertebral compression fractures. With 792 patients, this is the largest study to date in the treatment of compression fractures in multiple myeloma patients," he added.

"Vertebral compression fractures are very common in patients with multiple myeloma and cause severe pain and debilitation. Patients can experience compression of abdominal contents and a decrease in lung capacity, resulting in weight loss, anorexia and a reduced ability to perform normal daily functions," Erdem noted. "In our study, patients' pain from their spinal fractures was significantly reduced following vertebroplasty, resulting in about a 40 percent reduction in the use of narcotics for pain control," said Erdem, with half of the patients also reporting an improvement in their activity level following treatment.

About 20,000 Americans are diagnosed with multiple myeloma each year, making it the second most common blood cancer in the United States. Most patients are in their early sixties when diagnosed, and the disease is more common in men and African-Americans. Multiple myeloma is a cancer that begins in plasma cells, a type of white blood cell. These cells are part of the immune system, which helps protect the body from germs and other harmful substances. In time, myeloma cells collect in the bone marrow and in the solid parts of bone -- causing painful bone deterioration, typically in the drum-shaped bones of the spine, the vertebrae. Vertebral compression fractures occur when the internal scaffolding -- bone marrow -- is weakened due to the cancer, explained the co-author of "Vertebral Augmentation in the Treatment of Non-osteoporotic Vertebral Compression Fractures in 792 Patients With Multiple Myeloma."

Researchers at the University of Arkansas for Medical Sciences treated 2,715 non-osteoporotic vertebral compression fractures in 792 patients with multiple myeloma (45 percent women; average age, 63) over a six-year period. Of 2,715 non-osteoporotic vertebral compression fractures, 2,258 were treated by vertebroplasty and 457 were treated by kyphoplasty, a procedure in which a balloon is placed in the vertebrae (then inflated) and bone cement is applied.

In the study, the average pain intensity score for patients based on the 11-point visual analog scale dropped significantly from 7.0 to 2.7. In the study, 37 percent of patients reported a decrease in medication usage; 62 percent had no change; and 1 percent reported an increase in medication usage. Also, 48 percent of patients reported an improvement in their post-procedural activity level, and 83 percent would consider vertebroplasty or kyphoplasty again, if needed.


Story Source:

The above story is based on materials provided by Society of Interventional Radiology. Note: Materials may be edited for content and length.


Cite This Page:

Society of Interventional Radiology. "Vertebroplasty: Integral to treating back pain in blood marrow cancer patients." ScienceDaily. ScienceDaily, 15 March 2010. <www.sciencedaily.com/releases/2010/03/100315103804.htm>.
Society of Interventional Radiology. (2010, March 15). Vertebroplasty: Integral to treating back pain in blood marrow cancer patients. ScienceDaily. Retrieved April 24, 2014 from www.sciencedaily.com/releases/2010/03/100315103804.htm
Society of Interventional Radiology. "Vertebroplasty: Integral to treating back pain in blood marrow cancer patients." ScienceDaily. www.sciencedaily.com/releases/2010/03/100315103804.htm (accessed April 24, 2014).

Share This



More Health & Medicine News

Thursday, April 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Big Pharma Braces for M&A Wave

Big Pharma Braces for M&A Wave

Reuters - Business Video Online (Apr. 22, 2014) Big pharma on the move as Novartis boss, Joe Jimenez, tells Reuters about plans to transform his company via an asset exchange with GSK, and Astra Zeneca shares surge on speculation that Pfizer is looking for a takeover. Joanna Partridge reports. Video provided by Reuters
Powered by NewsLook.com
Study Says Most Crime Not Linked To Mental Illness

Study Says Most Crime Not Linked To Mental Illness

Newsy (Apr. 22, 2014) A new study finds most crimes committed by people with mental illness are not caused by symptoms of their illness or disorder. Video provided by Newsy
Powered by NewsLook.com
Hagel Gets Preview of New High-Tech Projects

Hagel Gets Preview of New High-Tech Projects

AP (Apr. 22, 2014) Defense Secretary Chuck Hagel is given hands-on demonstrations Tuesday of some of the newest research from DARPA _ the military's Defense Advanced Research Projects Agency program. (April 22) Video provided by AP
Powered by NewsLook.com
How Smaller Plates And Cutlery Could Make You Feel Fuller

How Smaller Plates And Cutlery Could Make You Feel Fuller

Newsy (Apr. 22, 2014) NBC's "Today" conducted an experiment to see if changing the size of plates and utensils affects the amount individuals eat. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins