Featured Research

from universities, journals, and other organizations

Genetic basis for health benefits of the 'Mediterranean diet'

Date:
April 22, 2010
Source:
BioMed Central
Summary:
Eating a diet rich in the phenolic components of virgin olive oil represses several pro-inflammatory genes. Researchers suggest that this partly explains the reduced risk of cardiovascular disease seen in people who eat a "Mediterranean diet."

Phenolic compounds in olive oil were found to positively modify genes involved in the inflammatory response, a team of researchers reports.
Credit: iStockphoto/Carla Guastella

Eating a diet rich in the phenolic components of virgin olive oil represses several pro-inflammatory genes. Researchers writing in the open access journal BMC Genomics suggest that this partly explains the reduced risk of cardiovascular disease seen in people who eat a 'Mediterranean diet'.

Related Articles


Francisco Perez-Jimenez from the University of Cordoba, Spain, led a team of researchers who studied the effects of eating a breakfast rich in phenol compounds on gene expression in 20 patients with metabolic syndrome, a common condition associated with increased risk of cardiovascular disease and type 2 diabetes. The study participants ate controlled breakfasts, and for six weeks before the study they had to avoid all drugs, vitamin tablets and other supplements.

Perez-Jimenez said: "We identified 98 differentially expressed genes when comparing the intake of phenol-rich olive oil with low-phenol olive oil. Several of the repressed genes are known to be involved in pro-inflammatory processes, suggesting that the diet can switch the activity of immune system cells to a less deleterious inflammatory profile, as seen in metabolic syndrome."

Phenols are micronutrients of olive oil; the extra-virgin varieties have a particularly large phenol fraction.

According to Perez-Jimenez, "These findings strengthen the relationship between inflammation, obesity and diet and provide evidence at the most basic level of healthy effects derived from virgin olive oil consumption in humans. It will be interesting to evaluate whether particular phenolic compounds carry these effects, or if they are the consequence of a synergic effect of the total phenolic fraction."


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Antonio Camargo, Juan Ruano, Juan M Fernandez, Laurence D Parnell, Anabel Jimenez, Monica Santos-Gonzalez, Carmen Marin, Pablo Perez-Martinez, Marino Uceda, Jose Lopez-Miranda and Francisco Perez-Jimenez. Gene expression changes in mononuclear cells from patients with metabolic syndrome after acute intake of phenol-rich virgin olive oil. BMC Genomics, 2010; (in press) [link]

Cite This Page:

BioMed Central. "Genetic basis for health benefits of the 'Mediterranean diet'." ScienceDaily. ScienceDaily, 22 April 2010. <www.sciencedaily.com/releases/2010/04/100419204628.htm>.
BioMed Central. (2010, April 22). Genetic basis for health benefits of the 'Mediterranean diet'. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2010/04/100419204628.htm
BioMed Central. "Genetic basis for health benefits of the 'Mediterranean diet'." ScienceDaily. www.sciencedaily.com/releases/2010/04/100419204628.htm (accessed October 31, 2014).

Share This



More Health & Medicine News

Friday, October 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Fauci Says Ebola Risk in US "essentially Zero"

Fauci Says Ebola Risk in US "essentially Zero"

AP (Oct. 30, 2014) NIAID Director Anthony Fauci said the risk of Ebola becoming an epidemic in the U.S. is essentially zero Thursday at the Washington Ideas Forum. He also said an Ebola vaccine will be tested in West Africa in the next few months. (Oct. 30) Video provided by AP
Powered by NewsLook.com
Nurse Defies Ebola Quarantine With Bike Ride

Nurse Defies Ebola Quarantine With Bike Ride

AP (Oct. 30, 2014) A nurse who vowed to defy Maine's voluntary quarantine for health care workers who treated Ebola patients followed through on her promise Thursday, leaving her home for an hour-long bike ride. (Oct. 30) Video provided by AP
Powered by NewsLook.com
Pot-Infused Edibles Raise Concerns in Colorado

Pot-Infused Edibles Raise Concerns in Colorado

AFP (Oct. 30, 2014) Colorado may have legalized marijuana for recreational use, but the debate around the decision still continues, with a recent - failed - attempt to ban cannabis-infused edibles. Duration: 01:53 Video provided by AFP
Powered by NewsLook.com
British Navy Ship Arrives in Sierra Leone With Ebola Aid

British Navy Ship Arrives in Sierra Leone With Ebola Aid

AFP (Oct. 30, 2014) The British ship RFA ARGUS arrived in Sierra Leone to deliver supplies and equipment to help the fight against Ebola. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins