Featured Research

from universities, journals, and other organizations

Invention regulates nerve cells electronically

Date:
May 22, 2010
Source:
Expertanswer (Expertsvar in Swedish)
Summary:
A major step toward being able to regulate nerve cells externally with the help of electronics has been taken by researchers in Sweden. The breakthrough is based on an ion transistor of plastic that can transport ions and charged biomolecules and thereby address and regulate cells.

Artist's concept of nerve cell signals.
Credit: iStockphoto

A major step toward being able to regulate nerve cells externally with the help of electronics has been taken by researchers at Linköping University and the Karolinska Institute in Sweden. The breakthrough is based on an ion transistor of plastic that can transport ions and charged biomolecules and thereby address and regulate cells.

The invention, which opens new avenues for controlling chemical signals, is being published in the coming issue of the scientific journal Proceedings of the National Academy of Sciences. The authors are Klas Tybrandt and Magnus Berggren of Linköping University, who developed the invention, and Karin Larsson and Agneta Richter-Dahlfors at the Karolinska Institute, who have used it in experiments with cultivated nerve cells.

The four scientists work at the OBOE Research Center, which is dedicated to the study and regulation of processes in living cells and tissue through the use of organic electronics.

Previously use has been made of nano-canals and nano-pores to actively control the concentration and transport of ions. But such components are difficult to produce and moreover function poorly when the salt content is high, which is a precondition in interaction with biological systems.

"To get around these problems, we exploited the similarity between ion-selective membranes -- plastics that only conduct ions of one charge -- and doped semiconductors, such as silicon. It was previously known that it is possible to produce diodes from such membranes. We took it a step further by joining two ion diodes into a transistor," says Klas Tybrandt, a doctoral candidate in organic electronics.

When an ion transistor was connected to cultivated nerve cells, it could be used to control the supply of the signal substance acetylcholin locally to the cells. The successful result demonstrates both that the component functions together with biological systems and that even tiny charged biomolecules can be transported without difficulty.

"Since the ion transistor is made of plastic, it can be integrated with other components we are developing. This means we can make use of inexpensive printing processes on flexible materials. We believe ion transistors will play a major role in various applications, such as the controlled delivery of drugs, lab-on-a-chip and sensors," says Magnus Berggren, Önnesjö professor of organic electronics.

The research center OBOE (organic bioelectronics) is funded by the Foundation for Strategic Research.


Story Source:

The above story is based on materials provided by Expertanswer (Expertsvar in Swedish). Note: Materials may be edited for content and length.


Journal Reference:

  1. K. Tybrandt, K. C. Larsson, A. Richter-Dahlfors, M. Berggren. Ion bipolar junction transistors. Proceedings of the National Academy of Sciences, 2010; DOI: 10.1073/pnas.0913911107

Cite This Page:

Expertanswer (Expertsvar in Swedish). "Invention regulates nerve cells electronically." ScienceDaily. ScienceDaily, 22 May 2010. <www.sciencedaily.com/releases/2010/05/100521191111.htm>.
Expertanswer (Expertsvar in Swedish). (2010, May 22). Invention regulates nerve cells electronically. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2010/05/100521191111.htm
Expertanswer (Expertsvar in Swedish). "Invention regulates nerve cells electronically." ScienceDaily. www.sciencedaily.com/releases/2010/05/100521191111.htm (accessed April 18, 2014).

Share This



More Health & Medicine News

Friday, April 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) — The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com
Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) — President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com
Is Apathy A Sign Of A Shrinking Brain?

Is Apathy A Sign Of A Shrinking Brain?

Newsy (Apr. 17, 2014) — A recent study links apathetic feelings to a smaller brain. Researchers say the results indicate a need for apathy screening for at-risk seniors. Video provided by Newsy
Powered by NewsLook.com
Could Even Casual Marijuana Use Alter Your Brain?

Could Even Casual Marijuana Use Alter Your Brain?

Newsy (Apr. 16, 2014) — A new study conducted by researchers at Northwestern and Harvard suggests even casual marijuana use can alter your brain. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins