Featured Research

from universities, journals, and other organizations

Adding nucleic acid testing to HIV screening may help identify more people with HIV

Date:
June 16, 2010
Source:
University of California - San Diego
Summary:
Community-based HIV testing programs generally use only HIV antibody testing, but nucleic acid testing can detect the presence of HIV earlier. Researchers studied more than 3,000 patients who sought HIV testing in community-based clinics in or near San Diego to examine the yield of testing with a rapid test plus NAT and to see whether patients would be willing to access their results by phone or computer.

Community-based HIV testing programs generally use only HIV antibody testing, but nucleic acid testing (NAT) can detect the presence of HIV earlier. Researchers at the University of California, San Diego School of Medicine studied more than 3,000 patients who sought HIV testing in community-based clinics in or near San Diego to examine the yield of testing with a rapid test plus NAT and to see whether patients would be willing to access their results by phone or computer.

Their study, published June 14 in the Annals of Internal Medicine, showed that NAT testing increased the HIV detection yield by 23%, and that a large majority of study participants received their negative test results by automated phone or internet systems.

"While the findings may not be generalized to all populations and testing programs, we did find that NAT programs that include automated systems for result reporting can increase case yield, especially in settings that cater to those men having sex with men," said the study's first author Sheldon Morris, MD, MPH, assistant clinical professor at UC San Diego's Antiviral Research Center.

Despite decades of prevention efforts in the U.S., the incidence rate of HIV has remained stable. Because the earliest stages of HIV infection represent a period of maximum infectiousness, early and accurate detection is critical to control the HIV epidemic.

"Extending the use of NAT to routine HIV testing programs might help decrease the HIV incidence rate by identifying persons with acute infection that would otherwise be missed through routine screening," said Morris. "In addition, automated reporting of negative results may prove an acceptable and less resource intense alternative to face-to-face reporting."

The patients were first tested for HIV with a rapid saliva test. If the result was positive, a counselor informed the patient and blood was obtained for a standard HIV test. If the result was negative, blood was obtained for a NAT. Nearly one quarter of persons with identified cases of HIV had positive results only by NAT testing. More than two-thirds of patients with negative NAT results retrieved them via computer or voicemail.

Most participants in the San Diego study (56%) and those with HIV (91%) were men having sex with men. According to the UCSD researchers, those with higher incomes, younger ages, no testing at substance abuse rehabilitation centers, no recent syphilis and no methamphetamine use were more likely to access negative NAT results by either internet or voicemail systems.

Contributors to the study were Susan J. Little, MD, Terry Cunningham, MAOM, Richard S. Garfein, MPH, PhD, Douglas D. Richman, MD, and Davey Smith, MD, MAS; all of UC San Diego School of Medicine.

The study was supported by funding from the California HIV/AIDS Research Program and the National Institutes of Health.


Story Source:

The above story is based on materials provided by University of California - San Diego. Note: Materials may be edited for content and length.


Cite This Page:

University of California - San Diego. "Adding nucleic acid testing to HIV screening may help identify more people with HIV." ScienceDaily. ScienceDaily, 16 June 2010. <www.sciencedaily.com/releases/2010/06/100614171859.htm>.
University of California - San Diego. (2010, June 16). Adding nucleic acid testing to HIV screening may help identify more people with HIV. ScienceDaily. Retrieved July 29, 2014 from www.sciencedaily.com/releases/2010/06/100614171859.htm
University of California - San Diego. "Adding nucleic acid testing to HIV screening may help identify more people with HIV." ScienceDaily. www.sciencedaily.com/releases/2010/06/100614171859.htm (accessed July 29, 2014).

Share This




More Health & Medicine News

Tuesday, July 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Ebola Virus Threatens West Africa

Deadly Ebola Virus Threatens West Africa

AP (July 28, 2014) West African nations and international health organizations are working to contain the largest Ebola outbreak in history. It's one of the deadliest diseases known to man, but the CDC says it's unlikely to spread in the U.S. (July 28) Video provided by AP
Powered by NewsLook.com
$15B Deal on Vets' Health Care Reached

$15B Deal on Vets' Health Care Reached

AP (July 28, 2014) A bipartisan deal to improve veterans health care would authorize at least $15 billion in emergency spending to fix a veterans program scandalized by long patient wait times and falsified records. (July 28) Video provided by AP
Powered by NewsLook.com
Two Americans Contract Ebola in Liberia

Two Americans Contract Ebola in Liberia

Reuters - US Online Video (July 28, 2014) Two American aid workers in Liberia test positive for Ebola while working to combat the deadliest outbreak of the virus ever. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins