Featured Research

from universities, journals, and other organizations

Increasing selenium intake may decrease bladder cancer risk

Date:
September 13, 2010
Source:
American Association for Cancer Research
Summary:
A common mineral may provide protection against bladder cancer.

A common mineral may provide protection against bladder cancer.

Related Articles


According to results of a study published in the September issue of Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research, selenium intake is associated with decreased risk of bladder cancer.

"The lower the levels of selenium, the higher the risk of developing bladder cancer," said lead researcher Nϊria Malats, M.D., Ph.D., leader of the Genetic and Molecular Epidemiology Group, Human Cancer Genetics Program, Spanish National Cancer Research Center.

Selenium is an essential micronutrient that is incorporated into about 25 proteins, called selenoproteins. Most of these selenoproteins are enzymes with antioxidant properties that prevent cellular damage caused by the by-products of oxygen metabolism, according to Malats.

The main dietary sources of this micronutrient are plant foods grown in selenium-rich soils, animals who graze on these soils and selenium-enriched products.

Using data from seven previously published studies, Malats and colleagues conducted a meta-analysis to evaluate selenium levels measured in serum and toenails and the risk of developing bladder cancer. The data included individuals mostly from the United States, but also from Belgium, Finland and the Netherlands.

The researchers noted a significant protective effect of selenium, mainly among women, which they believe may result from gender-specific differences in the mineral's accumulation and excretion in women.

"Although our results suggest a beneficial effect of high selenium intake for bladder cancer risk, more studies are needed to confirm these findings before an enforcement of high selenium intake is recommended," Malats said.

Cancer Epidemiology, Biomarkers & Prevention Editorial Board Member Elizabeth A. Platz, Sc.D., M.P.H., said, "these findings provide a valuable lead for what to do next to understand if there is a role for selenium supplementation in bladder cancer prevention."

The next research step is to address the dose-response relationship. Addressing this relationship is of public health importance for setting recommended daily intakes for selenium and for targeting subsets of the population for selenium supplementation, added Platz, who is a professor in the department of epidemiology at Johns Hopkins Bloomberg School of Public Health.


Story Source:

The above story is based on materials provided by American Association for Cancer Research. Note: Materials may be edited for content and length.


Journal Reference:

  1. A. F. S. Amaral, K. P. Cantor, D. T. Silverman, N. Malats. Selenium and Bladder Cancer Risk: a Meta-analysis. Cancer Epidemiology Biomarkers & Prevention, 2010; 19 (9): 2407 DOI: 10.1158/1055-9965.EPI-10-0544

Cite This Page:

American Association for Cancer Research. "Increasing selenium intake may decrease bladder cancer risk." ScienceDaily. ScienceDaily, 13 September 2010. <www.sciencedaily.com/releases/2010/08/100831134820.htm>.
American Association for Cancer Research. (2010, September 13). Increasing selenium intake may decrease bladder cancer risk. ScienceDaily. Retrieved November 29, 2014 from www.sciencedaily.com/releases/2010/08/100831134820.htm
American Association for Cancer Research. "Increasing selenium intake may decrease bladder cancer risk." ScienceDaily. www.sciencedaily.com/releases/2010/08/100831134820.htm (accessed November 29, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, November 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Rural India's Low-Cost Sanitary Pad Revolution

Rural India's Low-Cost Sanitary Pad Revolution

AFP (Nov. 28, 2014) — One man hopes his invention -– a machine that produces cheap sanitary pads –- will help empower Indian women. Duration: 01:51 Video provided by AFP
Powered by NewsLook.com
Research on Bats Could Help Develop Drugs Against Ebola

Research on Bats Could Help Develop Drugs Against Ebola

AFP (Nov. 28, 2014) — In Africa's only biosafety level 4 laboratory, scientists have been carrying out experiments on bats to understand how virus like Ebola are being transmitted, and how some of them resist to it. Duration: 01:18 Video provided by AFP
Powered by NewsLook.com
WHO Says Male Ebola Survivors Should Abstain From Sex

WHO Says Male Ebola Survivors Should Abstain From Sex

Newsy (Nov. 28, 2014) — WHO cites four studies that say Ebola can still be detected in semen up to 82 days after the onset of symptoms. Video provided by Newsy
Powered by NewsLook.com
Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins