Featured Research

from universities, journals, and other organizations

Method to detect bladder cancer earlier is under development

Date:
October 1, 2010
Source:
American Association for Cancer Research
Summary:
Scientists may have discovered a way to diagnose bladder cancer at its earliest and, therefore, most treatable stages by measuring the presence or absence of microRNA using already available laboratory tests.

Scientists may have discovered a way to diagnose bladder cancer at its earliest and, therefore, most treatable stages by measuring the presence or absence of microRNA using already available laboratory tests.

"Measuring expressions of microRNA in bodily fluid represents a very promising tool with widespread implications for screening," said Liana Adam, M.D., Ph.D., assistant professor in urology at The University of Texas MD Anderson Cancer Center.

Adam presented her findings at the Fourth AACR International Conference on Molecular Diagnostics in Cancer Therapeutic Development.

Bladder cancer is the fourth most common solid malignancy in men and the fifth most common overall, with an estimated 70,000 new cases and more than 14,000 deaths expected this year alone in the United States. Unfortunately, the majority of patients are asymptomatic.

Scientists are working with microRNAs, the non-coding part of DNA, because they are often tissue specific, stable and their presence or absence can be linked to known clinical parameters.

In this case, Adam and colleagues identified 79 separate microRNAs that had been previously shown to be dysregulated in the blood of individuals with bladder cancer. They took blood samples from 20 individuals with preoperative bladder cancer and 18 in a control group.

Using a collection of standard statistical models, they determined that measurement of these microRNAs was as accurate as the current gold standard of testing.

"This needs further validation, but we could reasonably use this method for widespread screening of bladder cancer," said Adam.


Story Source:

The above story is based on materials provided by American Association for Cancer Research. Note: Materials may be edited for content and length.


Cite This Page:

American Association for Cancer Research. "Method to detect bladder cancer earlier is under development." ScienceDaily. ScienceDaily, 1 October 2010. <www.sciencedaily.com/releases/2010/09/100928171420.htm>.
American Association for Cancer Research. (2010, October 1). Method to detect bladder cancer earlier is under development. ScienceDaily. Retrieved July 29, 2014 from www.sciencedaily.com/releases/2010/09/100928171420.htm
American Association for Cancer Research. "Method to detect bladder cancer earlier is under development." ScienceDaily. www.sciencedaily.com/releases/2010/09/100928171420.htm (accessed July 29, 2014).

Share This




More Health & Medicine News

Tuesday, July 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Generics Eat Into Pfizer's Sales

Generics Eat Into Pfizer's Sales

Reuters - Business Video Online (July 29, 2014) Pfizer, the world's largest drug maker, cut full-year revenue forecasts because generics could cut into sales of its anti-arthritis drug, Celebrex. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Nigeria Ups Ebola Stakes on 1st Death

Nigeria Ups Ebola Stakes on 1st Death

Reuters - Business Video Online (July 29, 2014) Nigerian authorities have shut and quarantined a Lagos hospital where a Liberian man died of the Ebola virus, the first recorded case of the highly-infectious disease in Africa's most populous economy. David Pollard reports Video provided by Reuters
Powered by NewsLook.com
Running 5 Minutes A Day Might Add Years To Your Life

Running 5 Minutes A Day Might Add Years To Your Life

Newsy (July 29, 2014) According to a new study, just five minutes of running or jogging a day could add years to your life. Video provided by Newsy
Powered by NewsLook.com
Ebola Outbreak Poses Little Threat To U.S.: CDC

Ebola Outbreak Poses Little Threat To U.S.: CDC

Newsy (July 29, 2014) The Ebola outbreak in West Africa poses little threat to Americans, according to officials with the Centers for Disease Control and Prevention. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins