Featured Research

from universities, journals, and other organizations

Could statins treat lung disease?

Date:
October 13, 2010
Source:
Queen's University, Belfast
Summary:
Researchers are investigating a potential new treatment for lung disease that could save many lives each year. They are studying how statins, drugs which are commonly used to treat high cholesterol, can be used to treat lung disease.

Researchers at Queen's University Belfast are investigating a potential new treatment for lung disease that could save many lives each year.

The research team is studying how statins, drugs which are commonly used to treat high cholesterol, can be used to treat lung disease.

There is currently no effective treatment for acute lung injury. The team hopes the work could boost survival rates for those who become critically ill and suffer lung failure after incidents such as road traffic accidents or severe infections.

Leading the research is Professor Danny McAuley from Queen's Centre for Infection and Immunity. He said: "When people are critically ill their lungs can fail. This is termed 'acute lung injury' and means that the lungs fill with water instead of air. Breathing becomes difficult and a ventilator is needed to take over.

"Statins have the potential to improve lung injury by reducing inflammation in the lung, reversing the damage and therefore decreasing the amount of water in the lungs. This helps fight infection."

The team includes Queen's researchers, Dr Celia O'Kane and Professor Cliff Taggart, along with Professor John Laffey from National University Ireland, Galway.

The research has the potential to free up healthcare resources and allow more people to return to the workplace sooner following spells in hospital.

Professor McAuley added: "There may be up to 45,000 cases of acute lung injury each year in the UK and Ireland and up to 22,000 deaths. Only around half of those who survive are able to return to work 12 months after discharge from hospital. After recovery from lung injury, patients can go on to experience a poorer quality of life and many are unable to look after themselves.

"But this treatment has the potential to reduce the impact of acute lung injury and the time patients need to stay in intensive care units. It could also significantly reduce the strain on hospital beds."

The study is being managed by staff from the Clinical Research Support Centre in the Belfast Health and Social Care Trust and has been supported by the infrastructure provided by the Northern Ireland Clinical Research Network. The Clinical Research Facility at NUI Galway is providing additional support. The study is taking place over four years in approximately 25 other intensive care units throughout the UK and Ireland.

The research is being funded by the Efficacy and Mechanism Evaluation programme which is funded by the Medical Research Council (MRC) and managed by the National Institute for Health Research (NIHR). The Health Research Board and the Intensive Care Society of Ireland have also provided additional funding.

Professor McAuley's previous research which lead to this study has been funded by the Health and Social Care Research and Development Division, Public Health Agency for Northern Ireland and REVIVE.


Story Source:

The above story is based on materials provided by Queen's University, Belfast. Note: Materials may be edited for content and length.


Cite This Page:

Queen's University, Belfast. "Could statins treat lung disease?." ScienceDaily. ScienceDaily, 13 October 2010. <www.sciencedaily.com/releases/2010/10/101013083303.htm>.
Queen's University, Belfast. (2010, October 13). Could statins treat lung disease?. ScienceDaily. Retrieved September 22, 2014 from www.sciencedaily.com/releases/2010/10/101013083303.htm
Queen's University, Belfast. "Could statins treat lung disease?." ScienceDaily. www.sciencedaily.com/releases/2010/10/101013083303.htm (accessed September 22, 2014).

Share This



More Health & Medicine News

Monday, September 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Liberia Pleads for Help to Fight Ebola

Liberia Pleads for Help to Fight Ebola

AP (Sep. 22, 2014) Liberia's finance minister is urging the international community to quickly follow through on pledges of cash to battle Ebola. Bodies are piling up in the capital Monrovia as the nation awaits more help. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Global Ebola Aid Increasing But Critics Say It's Late

Global Ebola Aid Increasing But Critics Say It's Late

Newsy (Sep. 21, 2014) More than 100 tons of medical supplies were sent to West Africa on Saturday, but aid workers say the global response is still sluggish. Video provided by Newsy
Powered by NewsLook.com
Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com
Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins