Featured Research

from universities, journals, and other organizations

Proton therapy safe, effective for early-stage lung cancer patients, study finds

Date:
October 20, 2010
Source:
American Society for Radiation Oncology
Summary:
Proton beam therapy is safe and effective and may be superior to other conventional treatments for Stage I inoperable non-small cell lung cancer (NSCLC) patients, according to a new study by researchers in Japan.

Proton beam therapy is safe and effective and may be superior to other conventional treatments for Stage I inoperable non-small cell lung cancer (NSCLC) patients, according to a study in the October issue of the International Journal of Radiation Oncology * Biology * Physics, the official journal of the American Society for Radiation Oncology (ASTRO).

Lung cancer is the number one cause of cancer death for men and women, according to the American Cancer Society. The standard treatment for early-stage lung cancer is surgery to remove all or part of the lung, but for patients with inoperable lung cancer, radiation is commonly used for treatment.

Researchers in Japan sought to determine if proton beam therapy was a good treatment option for patients with inoperable NSCLC versus conventional external beam radiation therapy and stereotactic body radiation therapy, which is a specialized type of external beam radiation therapy that uses focused radiation beams to target a well-defined tumor and relies on detailed imaging, computerized three-dimensional treatment planning and precise treatment setup to deliver the radiation dose with extreme accuracy.

Patients were treated with proton beam therapy from November 2001 to July 2008 with different doses given to peripherally located tumors and centrally located tumors. The two-year progression-free survival rates for those doses were 88.7 percent and 97 percent, respectively. The survival rate for stereotactic body radiotherapy is 54.7 percent at two years and the survival rates for conventional radiotherapy range from 6 percent to 31.4 percent at five years.

"Proton beam therapy is safe and effective, if not superior to other nonsurgical modalities, for treating patients with inoperable Stage I NSCLC," Hidetsugu Nakayama, M.D., Ph.D., lead author of the study and a physician at the Proton Medical Research Center in Tennoudai, Tsukuba, Ikbaraki, Japan, said. "The randomized clinical trial that compares proton beam therapy with stereotactic body radiotherapy is needed to clarify survival benefit."


Story Source:

The above story is based on materials provided by American Society for Radiation Oncology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Hidetsugu Nakayama, Hiroaki Satoh, Koichi Kurishima, Hiroichi Ishikawa, Koichi Tokuuye. High-Dose Conformal Radiotherapy for Patients With Stage III Non–Small-Cell Lung Carcinoma. International Journal of Radiation Oncology * Biology * Physics, 2010; 78 (3): 645 DOI: 10.1016/j.ijrobp.2009.08.037

Cite This Page:

American Society for Radiation Oncology. "Proton therapy safe, effective for early-stage lung cancer patients, study finds." ScienceDaily. ScienceDaily, 20 October 2010. <www.sciencedaily.com/releases/2010/10/101019171805.htm>.
American Society for Radiation Oncology. (2010, October 20). Proton therapy safe, effective for early-stage lung cancer patients, study finds. ScienceDaily. Retrieved April 23, 2014 from www.sciencedaily.com/releases/2010/10/101019171805.htm
American Society for Radiation Oncology. "Proton therapy safe, effective for early-stage lung cancer patients, study finds." ScienceDaily. www.sciencedaily.com/releases/2010/10/101019171805.htm (accessed April 23, 2014).

Share This



More Health & Medicine News

Wednesday, April 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Big Pharma Braces for M&A Wave

Big Pharma Braces for M&A Wave

Reuters - Business Video Online (Apr. 22, 2014) Big pharma on the move as Novartis boss, Joe Jimenez, tells Reuters about plans to transform his company via an asset exchange with GSK, and Astra Zeneca shares surge on speculation that Pfizer is looking for a takeover. Joanna Partridge reports. Video provided by Reuters
Powered by NewsLook.com
How Smaller Plates And Cutlery Could Make You Feel Fuller

How Smaller Plates And Cutlery Could Make You Feel Fuller

Newsy (Apr. 22, 2014) NBC's "Today" conducted an experiment to see if changing the size of plates and utensils affects the amount individuals eat. Video provided by Newsy
Powered by NewsLook.com
How to Master Motherhood With the Best Work/Life Balance

How to Master Motherhood With the Best Work/Life Balance

TheStreet (Apr. 22, 2014) In the U.S., there are more than 11 million couples trying to conceive at any given time. From helping celebrity moms like Bethanny Frankel to ordinary soon-to-be-moms, TV personality and parenting expert, Rosie Pope, gives you the inside scoop on mastering motherhood. London-born entrepreneur Pope is the creative force behind Rosie Pope Maternity and MomPrep. She explains why being an entrepreneur offers the best life balance for her and tips for all types of moms. Video provided by TheStreet
Powered by NewsLook.com
Catching More Than Fish: Ugandan Town Crippled by AIDS

Catching More Than Fish: Ugandan Town Crippled by AIDS

AFP (Apr. 22, 2014) The village of Kasensero on the shores of Lake Victoria was where HIV-AIDS was first discovered in Uganda. Its transient population of fishermen and sex workers means the nationwide programme to combat the virus has had little impact. Duration: 02:30 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins