Featured Research

from universities, journals, and other organizations

Pre-eclampsia: Early urine test predicts pregnancy complication

Date:
November 29, 2010
Source:
American Society of Nephrology
Summary:
Pre-eclampsia affects approximately 5% of pregnancies and can pose serious health concerns for mother and child. Some patients develop severe disease associated with kidney, liver, and neurological problems. The condition is characterized by high blood pressure and the loss of protein in the urine during the second half of pregnancy.

Pre-eclampsia affects approximately 5% of pregnancies and can pose serious health concerns for mother and child. Some patients develop severe disease associated with kidney, liver, and neurological problems. The condition is characterized by high blood pressure and the loss of protein in the urine during the second half of pregnancy.

Related Articles


Matt Hall, MBChB (Leicester General Hospital and the University of Leicester, United Kingdom) and colleagues conducted a study to see if analyzing the protein content of pregnant women's urine before the 20th week of pregnancy might predict pre-eclampsia. The researchers recruited 145 patients from a high-risk obstetric outpatient clinic; 11 (7.6%) developed pre-eclampsia, 10 at >37 weeks into the pregnancy and one at 31 weeks. An analysis of urine samples obtained prior to week 20 revealed a panel of 5 proteins that correctly predicted pre-eclampsia with 92% accuracy. "Our study suggests that changes in levels of certain proteins in the urine early in pregnancy can predict who will develop pre-eclampsia," said Dr. Hall. "Early identification will allow focused monitoring of those women and timely delivery of their babies, as well as reassurance for women at low risk."

Study co-authors include Paul Bosio, MD (Sandwell and West Birmingham NHS Trust, in Birmingham, the United Kingdom), Jonathan Barratt, MD, PhD; Nigel Brunskill, MD, PhD; Susan Carr MD (Leicester General Hospital and the University of Leicester); and Karen Molyneux, PhD (University of Leicester, in the United Kingdom).

Disclosures: The research was funded with pharmaceutical company support as well as clinical revenue support. The authors reported no other financial disclosures.

The study abstract, "An Early Pregnancy Urinary Proteomic Fingerprint Accurately Predicts Later Pre-Eclampsia," [F-FC223] was presented as an oral presentation on November 19, 2010 at the Colorado Convention Center in Denver, CO.


Story Source:

The above story is based on materials provided by American Society of Nephrology. Note: Materials may be edited for content and length.


Cite This Page:

American Society of Nephrology. "Pre-eclampsia: Early urine test predicts pregnancy complication." ScienceDaily. ScienceDaily, 29 November 2010. <www.sciencedaily.com/releases/2010/11/101121122607.htm>.
American Society of Nephrology. (2010, November 29). Pre-eclampsia: Early urine test predicts pregnancy complication. ScienceDaily. Retrieved January 31, 2015 from www.sciencedaily.com/releases/2010/11/101121122607.htm
American Society of Nephrology. "Pre-eclampsia: Early urine test predicts pregnancy complication." ScienceDaily. www.sciencedaily.com/releases/2010/11/101121122607.htm (accessed January 31, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, January 31, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC: Get Vaccinated for Measles

CDC: Get Vaccinated for Measles

Reuters - US Online Video (Jan. 30, 2015) The CDC is urging people to get vaccinated for measles amid an outbreak that began at Disneyland and has now infected more than 90 people. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Obama To Outline New Plan For Personalized Medicine

Obama To Outline New Plan For Personalized Medicine

Newsy (Jan. 30, 2015) President Obama is expected to speak with drugmakers Friday about his Precision Medicine Initiative first introduced last week. Video provided by Newsy
Powered by NewsLook.com
NFL Concussions Down; Still on Parents' Minds

NFL Concussions Down; Still on Parents' Minds

AP (Jan. 30, 2015) The NFL announced this week that the number of game concussions dropped by a quarter over last season. Still, the dangers of the sport still weigh on players, and parents&apos; minds. (Jan. 30) Video provided by AP
Powered by NewsLook.com
U.S. Wants to Analyze DNA from 1 Million People

U.S. Wants to Analyze DNA from 1 Million People

Reuters - US Online Video (Jan. 30, 2015) The U.S. has proposed analyzing genetic information from more than 1 million American volunteers to learn how genetic variants affect health and disease. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins