Featured Research

from universities, journals, and other organizations

World's fastest camera takes a new look at biosensing

Date:
December 1, 2010
Source:
National Physical Laboratory
Summary:
Scientists have developed a Megaframe Imager -- an ultrafast camera capable of recording images at the incredible rate of one million frames.

MEGAFRAME 32 x 32 Single Photon Avalanche Diode (SPAD) array fabricated in 0.13um STMICRO imaging CMOS technology.
Credit: Image courtesy of National Physical Laboratory

A European consortium comprising NPL, ST Microelectronics, the University of Edinburgh, and TU Delft has been involved in the development and application of the Megaframe Imager -- an ultrafast camera capable of recording images at the incredible rate of one million frames.

Related Articles


Faster, higher resolution cameras

Since the introduction of solid-state optical sensors, like those found in digital cameras, the main trend has been towards increasing the resolution (i.e. number of pixels) while miniaturising the chip.

However, the other factor is the number of frames the chip is capable of recording in a given time. Until recently, fast cameras (i.e. those capturing more than the 24 frames per second required for 'normal' video) were only used in niche markets in science and entertainment.

Ultrafast cameras

Now that higher-than-video speeds are achievable, a whole new range of previously unthinkable applications have emerged -- such as: cellular / sub-cellular imaging; neural imaging; biochemical sensors; DNA / protein microarray scanning; automotive collision studies; and high-sensitivity astronomical observations.

The Megaframe Imager uses an extremely sensitive single photon avalanche diode (SPAD) device, and bespoke on-chip intelligence and has shown for the first time that it could potentially be a powerful technology in biosensing.

Reporting in the Optical Society of America's new journal Biomedical Optics Express the research team have demonstrated detection of viral DNA binding events using fluoresence lifetime imaging at the very low target concentrations relevant in biosensing applications with acquisition times of less than 30 seconds.

DNA microarrays are important tools for biomolecular detection. Widely used for gene expression profiling, disease screening, mutation and forensic analysis, they also hold much promise for the future development of personalised drugs and point of care testing devices.

This work was funded by the EU's Sixth Framework programme.


Story Source:

The above story is based on materials provided by National Physical Laboratory. Note: Materials may be edited for content and length.


Journal Reference:

  1. Gerard Giraud, Holger Schulze, Day-Uei Li, Till T. Bachmann, Jason Crain, David Tyndall, Justin Richardson, Richard Walker, David Stoppa, Edoardo Charbon, Robert Henderson, and Jochen Arlt. Fluorescence lifetime biosensing with DNA microarrays and a CMOS-SPAD imager. Biomed. Opt., 1, 1302-1308 (2010) [link]

Cite This Page:

National Physical Laboratory. "World's fastest camera takes a new look at biosensing." ScienceDaily. ScienceDaily, 1 December 2010. <www.sciencedaily.com/releases/2010/11/101130104601.htm>.
National Physical Laboratory. (2010, December 1). World's fastest camera takes a new look at biosensing. ScienceDaily. Retrieved November 25, 2014 from www.sciencedaily.com/releases/2010/11/101130104601.htm
National Physical Laboratory. "World's fastest camera takes a new look at biosensing." ScienceDaily. www.sciencedaily.com/releases/2010/11/101130104601.htm (accessed November 25, 2014).

Share This


More From ScienceDaily



More Matter & Energy News

Tuesday, November 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Who Will Failed Nuclear Talks Hurt Most?

Who Will Failed Nuclear Talks Hurt Most?

Reuters - Business Video Online (Nov. 25, 2014) With no immediate prospect of sanctions relief for Iran, and no solid progress in negotiations with the West over the country's nuclear programme, Ciara Lee asks why talks have still not produced results and what a resolution would mean for both parties. Video provided by Reuters
Powered by NewsLook.com
Flying Enthusiast Converts Real-Life Aircraft Cockpit Into Simulator

Flying Enthusiast Converts Real-Life Aircraft Cockpit Into Simulator

Reuters - Innovations Video Online (Nov. 25, 2014) A virtual flying enthusiast converts parts of a written-off Airbus aircraft into a working flight simulator in his northern Slovenian home. Jim Drury reports. Video provided by Reuters
Powered by NewsLook.com
Car Park Solution for Flexible Green Energy

Car Park Solution for Flexible Green Energy

Reuters - Innovations Video Online (Nov. 24, 2014) A British solar power start-up says that by covering millions of existing car park spaces around the UK with flexible solar panels, the country's power problems could be solved. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Microsoft Adds Robot Guards, Ushers In Sci-Fi Apocalypse

Microsoft Adds Robot Guards, Ushers In Sci-Fi Apocalypse

Newsy (Nov. 23, 2014) Microsoft has robotic security guards working at its Silicon Valley Campus. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins