Featured Research

from universities, journals, and other organizations

Acid suppressive medication may increase risk of pneumonia

Date:
December 21, 2010
Source:
Canadian Medical Association Journal
Summary:
Using acid suppressive medications, such as proton pump inhibitors and histamine2 receptor antagonists, may increase the risk of developing pneumonia, states an article in Canadian Medical Association Journal.

Using acid suppressive medications, such as proton pump inhibitors and histamine2 receptor antagonists, may increase the risk of developing pneumonia, states an article in CMAJ (Canadian Medical Association Journal).

Related Articles


Acid suppressive drugs are the second leading medication worldwide, totaling over US$26 billion in sales in 2005. Recently, medical literature has looked at unrecognized side effects in popular medications and their impact on public health.

This systematic review, which incorporated all relevant studies on the association of acid suppressive medications and pneumonia that could be identified to August 2009, showed that out of every 200 inpatients being treated with acid suppressive medication one will develop pneumonia.

"Several previous studies have shown that treatment with acid-suppressive drugs might be associated with an increased risk of respiratory tract infections and community-acquired pneumonia in adults and children. However, the association between use of acid-suppressive drugs and risk of pneumonia has been inconsistent, writes Dr. Chun-Sick Eom and Dr. Sang Min Park, Department of Family Medicine, Seoul National University Hospital, Seoul, Korea with coauthors. "Given the widespread use of proton pump inhibitors and histamine2-receptor antagonists, clarifying the potential impact of acid-suppressive therapy on the risk of pneumonia is of great importance to public health."

Since 40-70% of hospitalized patients receive these drugs it may mean that deaths from hospital-acquired pneumonia could be caused by acid suppressive medications. The impact of acid suppressive medication on community-acquired pneumonia could be much greater.

The authors conclude that physicians should use caution when prescribing acid suppressive medication, especially in patients with a high risk of developing pneumonia.


Story Source:

The above story is based on materials provided by Canadian Medical Association Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. Chun-Sick Eom, Christie Y. Jeon, Ju-Won Lim, Eun-Geol Cho, Sang Min Park and Kang-Sook Lee. Use of acid-suppressive drugs and risk of pneumonia: systematic review and meta-analysis. CMAJ, December 20, 2010 DOI: 10.1503/cmaj.092129

Cite This Page:

Canadian Medical Association Journal. "Acid suppressive medication may increase risk of pneumonia." ScienceDaily. ScienceDaily, 21 December 2010. <www.sciencedaily.com/releases/2010/12/101220121058.htm>.
Canadian Medical Association Journal. (2010, December 21). Acid suppressive medication may increase risk of pneumonia. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2010/12/101220121058.htm
Canadian Medical Association Journal. "Acid suppressive medication may increase risk of pneumonia." ScienceDaily. www.sciencedaily.com/releases/2010/12/101220121058.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins