Featured Research

from universities, journals, and other organizations

Double doses of chicken pox vaccine most effective, researchers find

Date:
January 10, 2011
Source:
Yale University
Summary:
When vaccinating children against varicella (chicken pox), researchers have found, two doses are better than one. In fact, the odds of developing chicken pox were 95 percent lower in children who had received two doses of the vaccine compared with those who had received only one dose.

When vaccinating children against varicella (chicken pox), researchers at Yale School of Medicine have found, two doses are better than one. In fact, the odds of developing chicken pox were 95 percent lower in children who had received two doses of the vaccine compared with those who had received only one dose.

Related Articles


Published in the February 1 issue of Journal of Infectious Diseases, the study was led by Eugene D. Shapiro, M.D., professor in the Department of Pediatrics at Yale and his colleagues at Yale and Columbia universities.

The Centers for Disease Control and Prevention (CDC) began recommending a single dose of chicken pox vaccine for children ages 1 to 13 in 1995. The chicken pox rate fell drastically and studies showed that the effectiveness of one dose was 86 percent. But there was still a high rate of breakthrough illness in immunized children. The CDC changed the immunization policy for chicken pox in 2006, adding a second dose for children ages 4 to 6. In this study, Shapiro and his team showed that the effectiveness of two doses is 98.3 percent.

Past studies have suggested that two doses of varicella vaccine are linked to higher antibody levels than one dose, but this is the first study to assess the clinical effectiveness of two doses of the vaccine in the general population. In a survey of Connecticut children, Shapiro and his team discovered 71 cases of chicken pox in children ages 4 and older. None of these children had received two doses of vaccine; 66 (93 percent) had received one dose and five (7 percent) had received no vaccine.

"We weren't surprised to find that two doses of varicella vaccine are highly effective and are more likely to prevent varicella than a singe dose," said Shapiro. "The findings confirm that, at least in the short term, the policy of routinely administering two rather than one dose of varicella vaccine is sensible. Other countries that are routinely immunizing children with varicella vaccine may consider changing to a two-dose regimen."

Because it has only been four years since the CDC policy change, Shapiro also recommends that there be continued monitoring of the effectiveness of two doses to assure that its high degree of effectiveness is sustained.

Other authors on the study include Marietta Vazquez, M.D., Daina Esposito, Nancy Holabird, and James Dziura.


Story Source:

The above story is based on materials provided by Yale University. Note: Materials may be edited for content and length.


Journal Reference:

  1. E. D. Shapiro, M. Vazquez, D. Esposito, N. Holabird, S. P. Steinberg, J. Dziura, P. S. LaRussa, A. A. Gershon. Effectiveness of 2 Doses of Varicella Vaccine in Children. Journal of Infectious Diseases, 2011; 203 (3): 312 DOI: 10.1093/infdis/jiq052

Cite This Page:

Yale University. "Double doses of chicken pox vaccine most effective, researchers find." ScienceDaily. ScienceDaily, 10 January 2011. <www.sciencedaily.com/releases/2011/01/110105071019.htm>.
Yale University. (2011, January 10). Double doses of chicken pox vaccine most effective, researchers find. ScienceDaily. Retrieved April 21, 2015 from www.sciencedaily.com/releases/2011/01/110105071019.htm
Yale University. "Double doses of chicken pox vaccine most effective, researchers find." ScienceDaily. www.sciencedaily.com/releases/2011/01/110105071019.htm (accessed April 21, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, April 21, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Blue Bell Recalls All Products

Blue Bell Recalls All Products

AP (Apr. 21, 2015) Blue Bell Creameries voluntary recalled for all of its products after two samples of chocolate chip cookie dough ice cream tested positive for listeria, a potentially deadly bacteria. Blue Bell&apos;s President and CEO issued a video statement. (April 21) Video provided by AP
Powered by NewsLook.com
'Tutu Tuesdays' Brighten Faces at Kids' Hospital

'Tutu Tuesdays' Brighten Faces at Kids' Hospital

AP (Apr. 21, 2015) Doctors and nurses have started wearing ballet tutus every Tuesday to cheer up young hospital patients at a Florida hospital. It started with a request made by a nervous patient -- now, almost the entire staff is wearing the tutus. (April 21) Video provided by AP
Powered by NewsLook.com
Humanoid Robot Can Recognise and Interact With People

Humanoid Robot Can Recognise and Interact With People

Reuters - Innovations Video Online (Apr. 20, 2015) An ultra-realistic humanoid robot called &apos;Han&apos; recognises and interprets people&apos;s facial expressions and can even hold simple conversations. Developers Hanson Robotics hope androids like Han could have uses in hospitality and health care industries where face-to-face communication is vital. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Labour Party Warns Britain's Health Service 'on Life Support'

Labour Party Warns Britain's Health Service 'on Life Support'

AFP (Apr. 20, 2015) Britain&apos;s opposition Labour Party Monday claimed the National Health Service (NHS) was &apos;on life support&apos; as it turned its attention to the state-run service, which is a key issue for the UK&apos;s May 7 general election. Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins