Featured Research

from universities, journals, and other organizations

New marker for heart disease identified in study of firefighters

Date:
February 23, 2011
Source:
University of Calgary
Summary:
Researchers are shedding new light on an underlying cause of heart disease. A new study finds that endothelial dysfunction (blood vessel lining) can predict who is at risk for developing coronary heart disease. By identifying this new marker in patients, doctors may be able to intervene early to prevent the progression of heart disease.

A new study from the Libin Cardiovascular Institute at the University of Calgary's Faculty of Medicine is shedding light on an underlying cause of heart disease.

Published research led by UCalgary's Dr. Todd Anderson and his colleagues at four sites across Canada finds that endothelial dysfunction (blood vessel lining) can predict who is at risk for developing coronary heart disease. By identifying this new marker in patients doctors may be able to intervene early to prevent the progression of heart disease.

"The study has demonstrated that in addition to traditional cardiovascular risk factors, measures of blood vessel function are predictive of who goes on to develop cardiovascular complications," says Anderson who is the study's principal investigator, and director of the Libin Cardiovascular Institute of Alberta.

The observational study followed 1574 healthy firefighters over a period of ten years. At the beginning of the study each firefighter had an ultrasound of his brachial artery in the arm to measure blood vessel function and was then followed every six months for the 10 year period. Over the course of the study some of the study participants had cardiovascular events such as heart attacks and this allowed the research team to see what measurements correlated.

"The information obtained by these simple tests improves our ability to detect, among healthy individuals, those who will go on to have vascular events, with more precision and reliability than if we just tallied their traditional risk factors, as most clinicians do now," says Dr. Francois Charbonneau, a co-investigator and also from the University of Calgary's Faculty of Medicine and a member of the Libin Institute. "More research is required to see if these tests can be used in the population at large."

Wayne Morris is one of the firefighters who enrolled in the study. He's now 60-years-old, was followed by the researchers for the last decade and luckily had no cardiac events. "I enrolled in the project. I felt this was an extremely worthwhile study. Any study that will help the health professionals better predict who is at greater risk could be a life saver for people," he says.

Coronary artery diseases remain a major cause of death and disability in North America and can lead to heart attacks and congestive heart failure.

The study was published in the January 4th issue of Circulation, a journal of the American Heart Association.

The study was funded by Pfizer, Canadian Institutes of Health Research (CIHR), and the Heart and Stroke Foundation. Dr. Todd Anderson's research is also funded by Alberta Innovates -- Health Solutions.


Story Source:

The above story is based on materials provided by University of Calgary. Note: Materials may be edited for content and length.


Journal Reference:

  1. T. J. Anderson, F. Charbonneau, L. M. Title, J. Buithieu, M. S. Rose, H. Conradson, K. Hildebrand, M. Fung, S. Verma, E. M. Lonn. Microvascular Function Predicts Cardiovascular Events in Primary Prevention: Long-Term Results From the Firefighters and Their Endothelium (FATE) Study. Circulation, 2011; 123 (2): 163 DOI: 10.1161/CIRCULATIONAHA.110.953653

Cite This Page:

University of Calgary. "New marker for heart disease identified in study of firefighters." ScienceDaily. ScienceDaily, 23 February 2011. <www.sciencedaily.com/releases/2011/02/110222121915.htm>.
University of Calgary. (2011, February 23). New marker for heart disease identified in study of firefighters. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2011/02/110222121915.htm
University of Calgary. "New marker for heart disease identified in study of firefighters." ScienceDaily. www.sciencedaily.com/releases/2011/02/110222121915.htm (accessed April 18, 2014).

Share This



More Health & Medicine News

Friday, April 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com
Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins