Featured Research

from universities, journals, and other organizations

Re-formulation of microbicidal lubricants will help protect from HIV, study suggests

Date:
March 7, 2011
Source:
BioMed Central
Summary:
Microbicides can be used to protect against HIV, and other sexually transmitted diseases, either on their own or with the added protection of a condom. New research has investigated the use of lubricants, originally designed for vaginal application, and has developed and tested new, rectal-specific, formulations.

Microbicides can be used to protect against HIV, and other sexually transmitted diseases, either on their own or with the added protection of a condom. New research published by BioMed Central's open access journal AIDS Research and Therapy has investigated the use of lubricants, originally designed for vaginal application, and has developed and tested new, rectal specific, formulations.

Unprotected sex is one of the major ways that HIV spreads through the population. However most research has focused on the production of vaginal microbicides which, due to differences in pH, native bacterial populations (microflora), and thickness of the epithelium, may not be safe as rectal microbicides. Researchers at the Magee Woman's Research Institute, University of Pittsburgh, have shown that some mineral oil and silicone-based lubricants, but not the water-based ones they tested, significantly weakened the integrity of condoms making them more likely to break.

With this in mind Prof. Rohan's group has formulated four different lubricants, both water and lipid based, and in different formats, as a fluid or gel, which are currently being tested in clinical trials. Prof. Rohan said, "This is the first stage in the production of targeted microbicidal products. If successful these lubricants will provide a basis for the inclusion of different types of antibiotics, antivirals, and other drugs. Once completed these products will help reduce the incidence of sexually transmitted disease and bring hope in the fight to stop the spread of HIV.


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Lin Wang, Roger L Schnaare, Charlene Dezzutti, Peter A. Anton, and Lisa C. Rohan. Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations. AIDS Research and Therapy, 2011, 8:12 DOI: 10.1186/1742-6405-8-12

Cite This Page:

BioMed Central. "Re-formulation of microbicidal lubricants will help protect from HIV, study suggests." ScienceDaily. ScienceDaily, 7 March 2011. <www.sciencedaily.com/releases/2011/03/110307065359.htm>.
BioMed Central. (2011, March 7). Re-formulation of microbicidal lubricants will help protect from HIV, study suggests. ScienceDaily. Retrieved September 23, 2014 from www.sciencedaily.com/releases/2011/03/110307065359.htm
BioMed Central. "Re-formulation of microbicidal lubricants will help protect from HIV, study suggests." ScienceDaily. www.sciencedaily.com/releases/2011/03/110307065359.htm (accessed September 23, 2014).

Share This



More Health & Medicine News

Tuesday, September 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Liberia Pleads for Help to Fight Ebola

Liberia Pleads for Help to Fight Ebola

AP (Sep. 22, 2014) Liberia's finance minister is urging the international community to quickly follow through on pledges of cash to battle Ebola. Bodies are piling up in the capital Monrovia as the nation awaits more help. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Ebola Doctor Says Border Controls Critical

Ebola Doctor Says Border Controls Critical

AP (Sep. 22, 2014) A Florida doctor who helped fight the expanding Ebola outbreak in West Africa says the disease can be stopped, but only if nations quickly step up their response and make border control a priority. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Global Ebola Aid Increasing But Critics Say It's Late

Global Ebola Aid Increasing But Critics Say It's Late

Newsy (Sep. 21, 2014) More than 100 tons of medical supplies were sent to West Africa on Saturday, but aid workers say the global response is still sluggish. Video provided by Newsy
Powered by NewsLook.com
Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins