Featured Research

from universities, journals, and other organizations

Implant jab could solve the misery of back pain

Date:
May 19, 2011
Source:
University of Manchester
Summary:
Scientists have developed a biomaterial implant which could finally bring treatment, in the form of a jab, for chronic back pain.

Chronic lower back pain is a major problem for society -- behind only headaches as the most common neurological ailment -- and is frequently caused by degeneration of the intervertebral disc. Researchers have worked for many years to find a way of repairing the wear and tear on the lower back.

Now, in results published in the journal Soft Matter, they have discovered how to permanently replace the workings of the invertebral disc.

It is estimated that back pain affects 80% of people at some point in their lives. In the United States it is the most common cause of job-related disability, a leading contributor to people missing work.

The University of Manchester cross-faculty team have been working with microgel particles, which are swellable nanoscopic polymer particles, for a number of years.

Previously, they have demonstrated that an injectable fluid of these particles could transform into a gel that restored the mechanical properties of damaged model intervertebral discs.

Lead researcher Dr Brian Saunders, of the School of Materials, and his team have now succeeded in linking the microgel particles together to form injectable durable, elastic gels capable of sustaining large permanent changes in shape without breaking.

These improved injectable gels have much better mechanical properties than the first generation and should now display the necessary long-term durability required for an implanted device.

In this study the researchers -- who include PhD student Amir Milani and Dr Ruixue Liu -- have achieved an important milestone for producing injectable gels for minimally-invasive repair of IVD degeneration.

Dr Saunders said: ""Our team has made a breakthrough through innovative materials design that brings the prospect of an injectable gel for treating degeneration of the intervertebral disc a step closer.

Professor Tony Freemont, Head of Research in the School of Biomedicine, and co-author on the paper, added: "Degeneration of the intervertebral disc results in chronic back pain which costs the country billions of pounds per annum and causes untold misery for sufferers and their families.

"We have been working for 25 years to identify methods for treating degeneration of the intervertebral disc."

This work has been funded by the EPSRC and was recently awarded Proof-of-Principle (PoP) funding by The University of Manchester Intellectual Property Limited (UMIP).


Story Source:

The above story is based on materials provided by University of Manchester. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ruixue Liu, Amir H. Milani, Tony J. Freemont, Brian R. Saunders. Doubly crosslinked pH-responsive microgels prepared by particle inter-penetration: swelling and mechanical properties. Soft Matter, 2011; 7 (10): 4696 DOI: 10.1039/C1SM05216K

Cite This Page:

University of Manchester. "Implant jab could solve the misery of back pain." ScienceDaily. ScienceDaily, 19 May 2011. <www.sciencedaily.com/releases/2011/05/110519101238.htm>.
University of Manchester. (2011, May 19). Implant jab could solve the misery of back pain. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2011/05/110519101238.htm
University of Manchester. "Implant jab could solve the misery of back pain." ScienceDaily. www.sciencedaily.com/releases/2011/05/110519101238.htm (accessed August 1, 2014).

Share This




More Health & Medicine News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Despite Health Questions, E-Cigs Are Beneficial: Study

Despite Health Questions, E-Cigs Are Beneficial: Study

Newsy (July 31, 2014) Citing 81 previous studies, new research out of London suggests the benefits of smoking e-cigarettes instead of regular ones outweighs the risks. Video provided by Newsy
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins