Featured Research

from universities, journals, and other organizations

Key to making cancer-killing peptides

Date:
June 1, 2011
Source:
Aalto University
Summary:
Researchers have found the mechanism of action for cancer-cell-killing peptides. This research is expected to lead to better medication, in particular better treatments for leukemia, skin cancer, and infections caused by multi-resistant bacteria. Thanks to this new knowledge, it is hoped that future medical therapies will be more effective and have far fewer side effects. The first trials on patients are expected to take place over the next two years and the first finished products should be entering the market ten years from now.

Professor Paavo Kinnunen.
Credit: Image courtesy of Aalto University

Researchers from Aalto University have found the mechanism of action for cancer-cell-killing peptides. This breakthrough is expected to lead to better medication, in particular better treatments for leukemia, skin cancer, and infections caused by multi-resistant bacteria. Thanks to this new knowledge, it is hoped that future medical therapies will be more effective and have far fewer side effects. The first trials on patients are expected to take place over the next two years and the first finished products should be entering the market ten years from now.

Related Articles


The research has focused on peptides which target and lethally harm cancer cells. Cytotoxic peptides are short chains of amino acids that are able to penetrate and damage the lipid membrane surrounding individual cancer cells. By manipulating this response, researchers hope to cause cancer cells to die off and leave all other cells unharmed.

"Our research has shown that the mechanism by which these life-saving peptides trigger cell-death is similar to that utilized by peptides which are the culprit of certain neurodegenerative diseases," explains Professor Paavo Kinnunen, whose research team at the Department of Biomedical Engineering has made the breakthrough. The mechanism is similar, yet the effects are polar opposites -- either beneficial or lethal. Hence, the research results reached by Kinnunen and his team may affect not only the treatment of cancer but also the current understanding of neurodegenerative diseases such as Alzheimer's and Parkinson's diseases and their treatment.

Professor Kinnunen and his team have worked on cytotoxic peptides for a number of years. Interest in the topic is shared by research groups in many other universities, and other researchers have been able to confirm results reached by Kinnunen and his team.


Story Source:

The above story is based on materials provided by Aalto University. Note: Materials may be edited for content and length.


Cite This Page:

Aalto University. "Key to making cancer-killing peptides." ScienceDaily. ScienceDaily, 1 June 2011. <www.sciencedaily.com/releases/2011/05/110526091305.htm>.
Aalto University. (2011, June 1). Key to making cancer-killing peptides. ScienceDaily. Retrieved November 24, 2014 from www.sciencedaily.com/releases/2011/05/110526091305.htm
Aalto University. "Key to making cancer-killing peptides." ScienceDaily. www.sciencedaily.com/releases/2011/05/110526091305.htm (accessed November 24, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, November 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com
WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins