Featured Research

from universities, journals, and other organizations

Key to making cancer-killing peptides

Date:
June 1, 2011
Source:
Aalto University
Summary:
Researchers have found the mechanism of action for cancer-cell-killing peptides. This research is expected to lead to better medication, in particular better treatments for leukemia, skin cancer, and infections caused by multi-resistant bacteria. Thanks to this new knowledge, it is hoped that future medical therapies will be more effective and have far fewer side effects. The first trials on patients are expected to take place over the next two years and the first finished products should be entering the market ten years from now.

Professor Paavo Kinnunen.
Credit: Image courtesy of Aalto University

Researchers from Aalto University have found the mechanism of action for cancer-cell-killing peptides. This breakthrough is expected to lead to better medication, in particular better treatments for leukemia, skin cancer, and infections caused by multi-resistant bacteria. Thanks to this new knowledge, it is hoped that future medical therapies will be more effective and have far fewer side effects. The first trials on patients are expected to take place over the next two years and the first finished products should be entering the market ten years from now.

Related Articles


The research has focused on peptides which target and lethally harm cancer cells. Cytotoxic peptides are short chains of amino acids that are able to penetrate and damage the lipid membrane surrounding individual cancer cells. By manipulating this response, researchers hope to cause cancer cells to die off and leave all other cells unharmed.

"Our research has shown that the mechanism by which these life-saving peptides trigger cell-death is similar to that utilized by peptides which are the culprit of certain neurodegenerative diseases," explains Professor Paavo Kinnunen, whose research team at the Department of Biomedical Engineering has made the breakthrough. The mechanism is similar, yet the effects are polar opposites -- either beneficial or lethal. Hence, the research results reached by Kinnunen and his team may affect not only the treatment of cancer but also the current understanding of neurodegenerative diseases such as Alzheimer's and Parkinson's diseases and their treatment.

Professor Kinnunen and his team have worked on cytotoxic peptides for a number of years. Interest in the topic is shared by research groups in many other universities, and other researchers have been able to confirm results reached by Kinnunen and his team.


Story Source:

The above story is based on materials provided by Aalto University. Note: Materials may be edited for content and length.


Cite This Page:

Aalto University. "Key to making cancer-killing peptides." ScienceDaily. ScienceDaily, 1 June 2011. <www.sciencedaily.com/releases/2011/05/110526091305.htm>.
Aalto University. (2011, June 1). Key to making cancer-killing peptides. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2011/05/110526091305.htm
Aalto University. "Key to making cancer-killing peptides." ScienceDaily. www.sciencedaily.com/releases/2011/05/110526091305.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com
From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins