Featured Research

from universities, journals, and other organizations

Older adults with mild cognitive impairment may also have some functional impairment, study finds

Date:
June 9, 2011
Source:
JAMA and Archives Journals
Summary:
Difficulty remembering important dates and medications, and gathering paperwork, is more common in older individuals with mild cognitive impairment than in those with no cognition problems, according to a new report.

Difficulty remembering important dates and medications, and gathering paperwork, is more common in older individuals with mild cognitive impairment than in those with no cognition problems, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

Related Articles


According to background information in the article, mild cognitive impairment is a condition that includes some difficulty with cognition and, in the amnestic subtype (aMCI), difficulty with memory, but does not include considerable problems with daily tasks, work, or social activities. In some patients, this condition progresses to Alzheimer's disease (AD) or another form of dementia. So understanding the level of impairment a patient has is important, note the authors: "Identifying the extent and severity of functional deficits that typically occur in each disorder can aid in early diagnosis, help in estimating prognosis, and improve treatment strategies."

Patrick J. Brown, Ph.D., from the New York State Psychiatric Institute, and colleagues examined data from the Alzheimer's Disease Neuroimaging Initiative (ADNI). The authors evaluated 229 individuals with no cognitive problems, 394 who had a diagnosis of aMCI, and 193 who had a diagnosis of mild AD. The data included neuropsychological test results, participants' performance on the Pfeffer Functional Activities Questionnaire (FAQ), and brain-imaging studies.

Compared with the control group of those with no cognitive difficulty, most of the participants in the aMCI group and the AD group had difficulty with at least one type of function (7.9% vs. 72.3% and 97.4%, respectively). Two items that seemed to give the cognition-impaired participants significant problems were "assembling tax records, business affairs, or other papers" and "remembering appointments, family occasions, holidays, and medications." In the aMCI and AD groups, individuals who had the most difficulty functioning also tended to score worse on cognition tests, have smaller hippocampal volumes, and express the apolipoprotein ε4 allele.

The results, write the researchers, may help physicians better recognize whether patients with aMCI are likely to advance to dementia. "These findings show that even mild disruptions in daily functioning may be an important clinical indicator of disease and represent the latter phases of disease progression within the MCI classification system for cognitive impairment," they explain. More research into when and how trouble with functioning happens is needed, add the authors.


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Journal Reference:

  1. P. J. Brown, D. P. Devanand, X. Liu, E. Caccappolo. Functional Impairment in Elderly Patients With Mild Cognitive Impairment and Mild Alzheimer Disease. Archives of General Psychiatry, 2011; 68 (6): 617 DOI: 10.1001/archgenpsychiatry.2011.57

Cite This Page:

JAMA and Archives Journals. "Older adults with mild cognitive impairment may also have some functional impairment, study finds." ScienceDaily. ScienceDaily, 9 June 2011. <www.sciencedaily.com/releases/2011/06/110606171412.htm>.
JAMA and Archives Journals. (2011, June 9). Older adults with mild cognitive impairment may also have some functional impairment, study finds. ScienceDaily. Retrieved March 6, 2015 from www.sciencedaily.com/releases/2011/06/110606171412.htm
JAMA and Archives Journals. "Older adults with mild cognitive impairment may also have some functional impairment, study finds." ScienceDaily. www.sciencedaily.com/releases/2011/06/110606171412.htm (accessed March 6, 2015).

Share This


More From ScienceDaily



More Mind & Brain News

Friday, March 6, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Former NFL Players Donate Brains to Science

Former NFL Players Donate Brains to Science

Reuters - US Online Video (Mar. 3, 2015) Super Bowl champions Sidney Rice and Steve Weatherford donate their brains, post-mortem, to scientific research into repetitive brain trauma. Jillian Kitchener reports. Video provided by Reuters
Powered by NewsLook.com
Alzheimer's Protein Plaque Found In 20-Year-Olds

Alzheimer's Protein Plaque Found In 20-Year-Olds

Newsy (Mar. 3, 2015) Researchers found an abnormal protein associated with Alzheimer&apos;s disease in the brains of 20-year-olds. Video provided by Newsy
Powered by NewsLook.com
This Nasal Treatment Could Help Ease Migraine Pain

This Nasal Treatment Could Help Ease Migraine Pain

Newsy (Mar. 2, 2015) Researchers gave lidocaine to 112 patients, and about 88 percent of the subjects said they needed less migraine-relief medicine the next day. Video provided by Newsy
Powered by NewsLook.com
How Facebook Use Can Lead To Depression

How Facebook Use Can Lead To Depression

Newsy (Mar. 1, 2015) Margaret Duffy of the University of Missouri talks about her study on the social network and the envy and depression that Facebook use can cause. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins