Featured Research

from universities, journals, and other organizations

New technique advances bioprinting of cells

Date:
July 5, 2011
Source:
American Institute of Physics
Summary:
By extending pioneering acoustical work that applied sound waves to generate droplets from fluids, researchers have made encouraging preliminary findings at an early and crucial point in a stem cell's career known as embroid body formation.

Ever since an ordinary office inkjet printer had its ink cartridges swapped out for a cargo of cells about 10 years ago and sprayed out cell-packed droplets to create living tissue, scientists and engineers have never looked at office equipment in quite the same way. They dream of using a specialized bio-inkjet printer to grow new body parts for organ transplants or tissues for making regenerative medicine repairs to ailing bodies. Both these new therapies begin with a carefully printed mass of embryonic stem cells. And now there's progress on getting that initial mass of stem cells printed.

By extending his pioneering acoustical work that applied sound waves to generate droplets from fluids, Dr. Utkan Demirci and his team at Harvard Medical School's (Brigham and Women's Hospital) Bio-Acoustic Mems in Medicine Laboratory have made encouraging preliminary findings at an early and crucial point in a stem cell's career known as embroid body formation. Their research results appear in the journal Biomicrofluids, published by the American Institute of Physics.

Getting the embroid body formed correctly and without mechanical trauma is key to preserving the stem cells' astounding ability to develop into any desired tissue. Their new automated bioprinting approach appears to do this better than manual pipetting in the "hang-drop" method traditionally used.

Notes Dr. Demirci: "To have the capability to manipulate cells in a high-throughput environment reliably and repeatedly, whether it is a single cell or tens of thousands of cells in a single droplet, has the potential to enable potential solutions to many problems in medicine and engineering."

Three research results stand out:

  • Enhanced uniformity of size and ability to control droplet size. These are key variables because they determine how the embroid bodies will grow.
  • Achieving a scalable system that can print one cell or tens of thousands per droplet -- a level of precise manipulation not previously available.
  • Faster droplet formation. The new system delivers 160 droplets/seconds, versus 10 minutes for the hang-drop method.

The next step involves assessing the two methods to compare their effects on cell function. Says Dr. Demirci: "We are eager to take it to the next level."


Story Source:

The above story is based on materials provided by American Institute of Physics. Note: Materials may be edited for content and length.


Journal Reference:

  1. Feng Xu, BanuPriya Sridharan, ShuQi Wang, Umut Atakan Gurkan, Brian Syverud, Utkan Demirci. Embryonic stem cell bioprinting for uniform and controlled size embryoid body formation. Biomicrofluidics, 2011; 5 (2): 022207 DOI: 10.1063/1.3580752

Cite This Page:

American Institute of Physics. "New technique advances bioprinting of cells." ScienceDaily. ScienceDaily, 5 July 2011. <www.sciencedaily.com/releases/2011/07/110701121629.htm>.
American Institute of Physics. (2011, July 5). New technique advances bioprinting of cells. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2011/07/110701121629.htm
American Institute of Physics. "New technique advances bioprinting of cells." ScienceDaily. www.sciencedaily.com/releases/2011/07/110701121629.htm (accessed August 1, 2014).

Share This




More Health & Medicine News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Despite Health Questions, E-Cigs Are Beneficial: Study

Despite Health Questions, E-Cigs Are Beneficial: Study

Newsy (July 31, 2014) Citing 81 previous studies, new research out of London suggests the benefits of smoking e-cigarettes instead of regular ones outweighs the risks. Video provided by Newsy
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins