Featured Research

from universities, journals, and other organizations

Delayed access to tertiary care associated with higher death rate from type of pulmonary fibrosis

Date:
July 1, 2011
Source:
Columbia University Medical Center
Summary:
Idiopathic pulmonary fibrosis -- scarring and thickening of the lungs from unknown causes -- is the predominant condition leading to lung transplantation nationwide. Researchers confirmed that delayed access to a tertiary care center for IPF is associated with a higher risk of death.

Idiopathic pulmonary fibrosis (IPF) -- scarring and thickening of the lungs from unknown causes -- is the predominant condition leading to lung transplantation nationwide. Columbia University Medical Center researchers confirmed that delayed access to a tertiary care center for IPF is associated with a higher risk of death.

Related Articles


The findings were published online in the American Journal of Respiratory and Critical Care Medicine on June 30, 2011.

A group led by Columbia researcher David J. Lederer followed 129 IPF patients at an academic medical center. They looked at the length of time from the onset of shortness of breath to the first visit to the center. A longer delay was associated with increased risk of death, independent of age, gender, socioeconomic status, lung capacity, disease severity, type of health insurance, or education. The researchers also found no association between the length of delay and the likelihood of the patient's receiving a lung transplant.

IPF leads to respiratory failure and death, usually within three years. It is a relatively rare disease, which afflicts 100,000 to 200,000 Americans, mostly over the age of 50. Characterized by shortness of breath upon exertion, it is often misdiagnosed, especially in people with other ailments.

A delay in making a correct diagnosis can lead to ineffective, or even harmful, treatments. For example, doctors sometimes still treat IPF with steroids, because the disease was originally thought to have an inflammatory component. Now scientists know that steroids are counterproductive. A delay in diagnosis can also delay evaluation for a lung transplant. Although research is underway on potential drug therapies, currently lung transplantation is the only effective treatment.

"The initial symptoms of IPF are subtle, and accurate diagnosis may not be feasible for community-based pulmonologists," explains Lederer, Herbert Irving Assistant Professor of Clinical Medicine and co-director of the New York-Presbyterian Hospital Interstitial Lung Disease Program and Lung Transplant Program.

For that reason, earlier access would be aided by improved methods of early detection. But until then, the recognition, or even suspicion, of IPF should prompt referral to a tertiary care center.

The study's authors are Daniela J Lamas (CUMC), Steven M. Kawut (University of Pennsylvania), Emilia Bagiella (CUMC), Nisha Philip (CUMC), Selim M. Arcasoy (CUMC), and David J. Lederer (CUMC).

The study was supported by the NIH, the Robert Wood Johnson Foundation, and Herbert and Florence Irving.


Story Source:

The above story is based on materials provided by Columbia University Medical Center. Note: Materials may be edited for content and length.


Journal Reference:

  1. D. J. Lamas, S. M. Kawut, E. Bagiella, N. Philip, S. M. Arcasoy, D. J. Lederer. Delayed Access and Survival in Idiopathic Pulmonary Fibrosis: a Cohort Study. American Journal of Respiratory and Critical Care Medicine, 2011; DOI: 10.1164/rccm.201104-0668OC

Cite This Page:

Columbia University Medical Center. "Delayed access to tertiary care associated with higher death rate from type of pulmonary fibrosis." ScienceDaily. ScienceDaily, 1 July 2011. <www.sciencedaily.com/releases/2011/07/110701132404.htm>.
Columbia University Medical Center. (2011, July 1). Delayed access to tertiary care associated with higher death rate from type of pulmonary fibrosis. ScienceDaily. Retrieved November 22, 2014 from www.sciencedaily.com/releases/2011/07/110701132404.htm
Columbia University Medical Center. "Delayed access to tertiary care associated with higher death rate from type of pulmonary fibrosis." ScienceDaily. www.sciencedaily.com/releases/2011/07/110701132404.htm (accessed November 22, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, November 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com
Raw: Paralyzed Marine Walks With Robotic Braces

Raw: Paralyzed Marine Walks With Robotic Braces

AP (Nov. 21, 2014) Marine Corps officials say a special operations officer left paralyzed by a sniper's bullet in Afghanistan walked using robotic leg braces in a ceremony to award him a Bronze Star. (Nov. 21) Video provided by AP
Powered by NewsLook.com
Milestone Birthdays Can Bring Existential Crisis, Study Says

Milestone Birthdays Can Bring Existential Crisis, Study Says

Newsy (Nov. 21, 2014) Researchers find that as people approach new decades in their lives they make bigger life decisions. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins